Evidence map›Paper›PMID 33197895›Full record

ArticleAging2020

The DLG1-AS1/miR-497/YAP1 axis regulates papillary thyroid cancer progression.

Yong Huang, KeWei Zhang, Yinghua Li, Yuyin Dai, Hongguang Zhao

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yong HuangDepartment of Nuclear Medicine, The First Hospital of Jilin University, Changchun 130021, China.
KeWei ZhangDepartment of Thoracic Surgery, The First Hospital of Jilin University, Changchun 130021, China.
Yinghua LiDepartment of Nuclear Medicine, The First Hospital of Jilin University, Changchun 130021, China.
Yuyin DaiDepartment of Nuclear Medicine, The First Hospital of Jilin University, Changchun 130021, China.
Hongguang ZhaoDepartment of Nuclear Medicine, The First Hospital of Jilin University, Changchun 130021, China.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The long non-coding RNA (lncRNA), DLG1-AS1, is upregulated in papillary thyroid cancer (PTC) tissues and cell lines. Here, we found that increased expression of DLG1-AS1 caused lymph node metastasis and advanced tumor-node-metastasis (TNM) stage. DLG1-AS1 knockdown inhibited proliferation, invasion, and migration of PTC cells, and impaired tumorigenesis

Indexed as

Adaptor Proteins, Signal TransducingAnimalsCell Line, TumorCell MovementCell ProliferationDisease ProgressionFemaleGene Expression Regulation, NeoplasticHumansMaleMice, Inbred BALB CMice, NudeMicroRNAsMiddle AgedNeoplasm InvasivenessRNA, Long NoncodingAdaptor Proteins, Signal TransducingMicroRNAsMIRN497 microRNA, humanRNA, Long NoncodingTranscription FactorsYAP1 protein, humanYAP-Signaling ProteinsDLG1-AS1lncRNAmiR-497papillary thyroid cancerYAP1

Identifiers

PMID33197895
PMCPMC7746333
OpenAlexW3105311665

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.