Evidence map›Paper›PMID 33200626›Full record

Trial reportFood and nutrition bulletin2020

The Effect of Calcium Supplementation on Body Weight Before and During Pregnancy in Women Enrolled in the WHO Calcium and Preeclampsia Trial.

Gabriela Cormick, Ana Pilar Betrán, Janetta Harbron, Armando Seuc, Cintia White, James M Roberts, Jose M Belizán, G Justus Hofmeyr

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Food and nutrition bulletin, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 4 pooled it
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Calcium supplementation for people with overweight or obesity.The Cochrane database of systematic reviews · 2024
    Pooled it
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 7 countries.

Gabriela CormickDepartment of Mother and Child Health Research, 172472Institute for Clinical Effectiveness and Health Policy (IECS-CONICET), Buenos Aires, Argentina.ORCID 0000-0001-7958-7358
Ana Pilar BetránHRP-UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction, Department of Reproductive Health and Research, 3489World Health Organization, Geneva, Switzerland.
Janetta HarbronDepartment of Human Biology, Faculty of Health Sciences, 37716University of Cape Town, South Africa.
Armando Seuc217256Instituto Nacional de Higiene, Epidemiología y Microbiología, La Habana, Cuba.
Cintia WhiteDepartamento de Salud, 28224Universidad Nacional de La Matanza, San Justo, Argentina.
James M RobertsMagee-Womens Research Institute, Department of Obstetrics and Gynecology, Epidemiology and Clinical and Translational Research 6614University of Pittsburgh, PA, USA.
Jose M BelizánDepartment of Mother and Child Health Research, 172472Institute for Clinical Effectiveness and Health Policy (IECS-CONICET), Buenos Aires, Argentina.
G Justus HofmeyrEffective Care Research Unit, 37707Universities of the Witwatersrand, Walter Sisulu and Fort Hare, South Africa.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARInstituto Nacional de Higiene, Epidemiología y Microbiología · CUUniversidad Nacional de La Matanza · ARUniversity of Botswana · BWUniversity of Cape Town · ZAUniversity of Pittsburgh · USWorld Health Organization - Pakistan · PK

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionObesity is a major and challenging public health problem. The aim of this substudy is to evaluate the effect of calcium supplementation on body weight in women recruited in the Calcium and Preeclampsia trial.

methodsWomen were recruited before pregnancy and randomized to receive a calcium supplement containing 500 mg of elemental calcium or placebo until 20 weeks' gestation; all women received 1.5 g from 20 weeks until delivery.

resultsA total of 630 women conceived during the study, 322 allocated to calcium and 308 to placebo. Among these, 230 allocated to calcium and 227 allocated to placebo had information on body weight at baseline and at 8 weeks' gestation. During the study period, women allocated to calcium had a mean weight increase of 1.1 (SD ±5.5) kg, whereas those allocated to placebo had a mean increase of 1.5 (SD ±6.1) kg, a mean difference of 0.4 kg (95% -0.4 (-1.4 to 0.6);

conclusionThe smaller increase in body weight found in women supplemented with 500 mg elemental calcium daily is quantitatively consistent with previous studies. However, in this study, the difference was not statistically significant.

Indexed as

Preconception CarePrenatal CareAdultArgentinaCalcium, DietaryDietary SupplementsFemaleHumansMaternal Nutritional Physiological PhenomenaPre-EclampsiaPregnancySouth AfricaTreatment OutcomeWeight GainWorld Health OrganizationZimbabweCalcium, Dietarybody mass indexcalciumobesitypregnancysupplementation

Identifiers

PMID33200626
PMCPMC11951462
OpenAlexW3105163917

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.