Evidence map›Paper›PMID 33204476›Full record

ArticleRoyal Society open science2020

Adaptation of the carbamoyl-phosphate synthetase enzyme in an extremophile fish.

Lewis J White, Gemma Sutton, Asilatu Shechonge, Julia J Day, Kanchon K Dasmahapatra, Mary E Pownall

Open access · goldAbstract read
In one paragraph

Article in Royal Society open science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Early onset of urea synthesis and ammonia detoxification pathways in three terrestrially developing frogs.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2023
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Lewis J WhiteBiology Department, University of York, York YO10 5DD, UK.ORCID 0000-0002-8764-2051
Gemma SuttonBiology Department, University of York, York YO10 5DD, UK.ORCID 0000-0002-0459-0912
Asilatu ShechongeTanzania Fisheries Research Institute, PO BOX 98, Kyela, Mbeya, Tanzania.
Julia J DayDepartment of Genetics, Evolution and Environment, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK.
Kanchon K DasmahapatraBiology Department, University of York, York YO10 5DD, UK.
Mary E PownallBiology Department, University of York, York YO10 5DD, UK.
University of York · GBTanzania Fisheries Research Institute · TZUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetrapods and fish have adapted distinct carbamoyl-phosphate synthase (CPS) enzymes to initiate the ornithine urea cycle during the detoxification of nitrogenous wastes. We report evidence that in the ureotelic subgenus of extremophile fish

Indexed as

Alcolapiacarbamoyl-phosphate synthetaseextremophilefishurea

Identifiers

PMID33204476
PMCPMC7657897
OpenAlexW3092889909

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.