Evidence map›Paper›PMID 33204697›Full record

ArticleBioMed research international2020

Differential Expression of mRNAs in Peripheral Blood Related to Prodrome and Progression of Alzheimer's Disease.

Weishuang Xue, Jinwei Li, Kailei Fu, Weiyu Teng

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Weishuang XueDepartment of Neurology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Jinwei LiDepartment of Neurology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Kailei FuDepartment of Neurology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Weiyu TengDepartment of Neurology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China.ORCID https://orcid.org/0000-0001-6972-8663
First Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease that affects the quality of life of elderly individuals, while the pathogenesis of AD is still unclear. Based on the bioinformatics analysis of differentially expressed genes (DEGs) in peripheral blood samples, we investigated genes related to mild cognitive impairment (MCI), AD, and late-stage AD that might be used for predicting the conversions.

Indexed as

Alzheimer DiseaseCognitive DysfunctionDatabases, GeneticGene Expression ProfilingGene OntologyHumansProtein Interaction MapsRNA, MessengerSoftwareRNA, Messenger

Identifiers

PMID33204697
PMCPMC7648929
OpenAlexW3095722428

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.