ArticleScience (New York, N.Y.)2020
A marine microbiome antifungal targets urgent-threat drug-resistant fungi.
Abstract read
In one paragraph
Article in Science (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.
0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
94 citing papers in PubMed.
- Characterization of Sec14 Domain-Containing Proteins in the Malaria Parasite Plasmodium falciparum.Molecular microbiology · 2026Article
- Article
- Antifungal turbinmicin alters functional vesicle cargo.Antimicrobial agents and chemotherapy · 2026Article
- Innovation in antifungal therapy.EMBO molecular medicine · 2026Review
- Candida Infections in Marine Mammals: Epidemiology, Antifungal Resistance, and One Health Implications.Animals : an open access journal from MDPI · 2026Review
- The Four Critical Priority Fungi According to the World Health Organization and the Hope for New Therapies: A Focus on Cell Wall Antifungal Targets.Journal of fungi (Basel, Switzerland) · 2026Review
- The emerging pathogen Candida auris: host interactions and disease drivers.Journal of biomedical science · 2026Review
- Zinc peroxide-copper bimetallic nanozyme with self-activated ROS and cuproptosis for superficial antifungal therapy.Journal of nanobiotechnology · 2026Article
- A noncanonical transcriptional regulation in natural product biosynthesis.Nucleic acids research · 2026Article
- Effective combinatorial antifungal therapy using a host defense peptide mimic that self-assembles into delivery micelles.Nature biotechnology · 2026Article
- Xenosiderophore transporter gene expression and clade-specific filamentation in Candida auris killifish (Aphanius dispar) infection.Communications biology · 2025Article
- The antifungal mechanism of EntV-derived peptides is associated with a reduction in extracellular vesicle release.PLoS pathogens · 2025Article
- Optimizing therapeutic efficacy of antifungal peptides via strategic terminal amino acid modification.Journal of advanced research · 2025Article
- Characterizing antimicrobial activity of environmentalmSphere · 2025Article
- Vesicle inhibition reducesAntimicrobial agents and chemotherapy · 2025Article
- Inhibitory effect of copper chelators on the budding inAntimicrobial agents and chemotherapy · 2025Article
- Synergistic antifungal activity of minocycline as an effective augmenting agent of fluconazole against drug-resistantMicrobiology spectrum · 2025Article
- Lipid droplets restrict phagosome formation in antifungal immunity.Cellular & molecular immunology · 2025Article
- Mission Tara Microplastics: a holistic set of protocols and data resources for the field investigation of plastic pollution along the land-sea continuum in Europe.Environmental science and pollution research international · 2025Article
- Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
22 authors.
Fan Zhang *Pharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0001-9732-1123
Miao Zhao *Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-7851-6758
Doug R BraunPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.
Spencer S EricksenSmall Molecule Screening Facility, University of Wisconsin Carbone Cancer Center, Madison, WI, USA.ORCID 0000-0003-4907-1160
Jeff S PiotrowskiYumanity Therapeutics, Cambridge, MA, USA.ORCID 0000-0001-8490-8339
Justin NelsonYumanity Therapeutics, Cambridge, MA, USA.
Jian PengDepartment of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0002-1736-2978
Gene E AnanievSmall Molecule Screening Facility, University of Wisconsin Carbone Cancer Center, Madison, WI, USA.
Shaurya ChananaPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-3021-2210
Kenneth BarnsPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-1856-4280
Jen FossenDepartment of Medicine, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-2413-5618
Hiram SanchezDepartment of Medicine, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-6286-650X
Marc G ChevretteDepartment of Genetics, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-7209-0717
Ilia A GuzeiDepartment of Chemistry, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-1976-7386
Changgui ZhaoPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.
Le GuoPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.
Weiping TangPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-0039-3196
Cameron R CurrieDepartment of Genetics, University of Wisconsin-Madison, Madison, WI, USA.
Scott R RajskiPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-0238-8411
Anjon AudhyaDepartment of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-7828-5152
David R AndesDepartment of Medicine, University of Wisconsin-Madison, Madison, WI, USA. tim.bugni@wisc.edu dra@medicine.wisc.edu.ORCID 0000-0002-7927-9950
Tim S BugniPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI, USA. tim.bugni@wisc.edu dra@medicine.wisc.edu.ORCID 0000-0002-4502-3084
Funding
UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6MNovel antimicrobials targeting MDR pathogens from animal microbial symbiontsU19AI142720 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI ANDES, DAVID R · 2019 to 2023
$30.1MMetabolomics driven discovery of drug leads from symbiotic bacteriaU19AI109673 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI ANDES, DAVID R, CURRIE, CAMERON ROBERT · 2014 to 2018
$16.2MWATER DISTRIB:PHYSICAL PROPERT:PIZZA &LMPS MOZZARELLA CHEESES:EARLY STAGE MATURP41RR002301 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN LUTE · 1985 to 2011
$13.0MTR&D 3: TECHNOLOGY DEVELOPMENT FOR NMR STUDIES OF SMALL MOLECULES (METABOLOMICS, NATURAL PRODUCTS, METABOLITE-PROTEIN INTERACTIONS) pp.537-585 P41GM103399 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BUTCHER, SAMUEL E · 2012 to 2019
$9.4MVesicle-mediated drug resistance of Candida albicans biofilmR01AI073289 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI ANDES, DAVID R, MITCHELL, AARON P · 2008 to 2025
$7.9MMolecular mechanisms that regulate vesicle formation and transportR35GM134865 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Anjon Audhya · 2020 to 2026
$4.8MMolecular Mechanisms that Regulate Lysosomal Protein TransportR01GM088151 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI AUDHYA, ANJON · 2010 to 2019
$3.0MOmics approaches for natural products discoveryR01GM104192 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BUGNI, TIMOTHY S · 2013 to 2019
$2.0MRegulatory mechanisms that control vesicle secretion at the endoplasmic reticulumR01GM110567 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI AUDHYA, ANJON · 2015 to 2019
$1.8MIntegrated state-of-the-art LC-MS/NMR system for the University of WisconsinS10RR025062 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN LUTE · 2008 to 2008
$1.7MUpgrade of the NMRFAM 750 MHz NMR SpectrometerS10RR029220 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN LUTE · 2010 to 2010
$766kNCI NIH HHS P30 CA014520NCRR NIH HHS P41 RR002301NCRR NIH HHS S10 RR002781NCRR NIH HHS S10 RR008438NCRR NIH HHS S10 RR023438NCRR NIH HHS S10 RR025062NCRR NIH HHS S10 RR029220NIAID NIH HHS R01 AI073289NIAID NIH HHS U19 AI109673NIAID NIH HHS U19 AI142720NIGMS NIH HHS P41 GM103399NIGMS NIH HHS R01 GM088151NIGMS NIH HHS R01 GM104192NIGMS NIH HHS R01 GM110567NIGMS NIH HHS R35 GM134865
Abstract
New antifungal drugs are urgently needed to address the emergence and transcontinental spread of fungal infectious diseases, such as pandrug-resistant
Indexed as
Drug Resistance, Multiple, FungalAnimalsAntifungal AgentsBenzopyransCandidaCandidiasis, InvasiveDisease Models, AnimalFungal ProteinsIsoquinolinesMiceMicrobiotaMicromonosporaPhospholipid Transfer ProteinsUrochordataAntifungal AgentsBenzopyransFungal ProteinsIsoquinolinesPhospholipid Transfer Proteinsturbinmicin
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.