Evidence map›Paper›PMID 33214906›Full record

ArticleEnvironmental epigenetics2020

TCDD-induced multi- and transgenerational changes in the methylome of male zebrafish gonads.

Camille Akemann, Danielle N Meyer, Katherine Gurdziel, Tracie R Baker

Open access · goldAbstract read
In one paragraph

Article in Environmental epigenetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Endocrine Disrupting Agents: Toxicological Aspects on Male Reproduction.Reproductive sciences (Thousand Oaks, Calif.) · 2025
    Review
  3. Article
  4. Article
  5. Exposure to 3,3',4,4',5-Pentachlorobiphenyl (PCB126) Causes Widespread DNA Hypomethylation in Adult Zebrafish Testis.Toxicological sciences : an official journal of the Society of Toxicology · 2022
    Article
  6. Impact of Endocrine Disruptors upon Non-Genetic Inheritance.International journal of molecular sciences · 2022
    Review
  7. Challenging dogmas: How transgenerational epigenetics reshapes our views on life.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2022
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Camille AkemannDepartment of Pharmacology, Wayne State University, Detroit, 540 E. Canfield, Detroit, MI, 48201, USA.
Danielle N MeyerDepartment of Pharmacology, Wayne State University, Detroit, 540 E. Canfield, Detroit, MI, 48201, USA.
Katherine GurdzielSchool of Medicine, Applied Genome Technology Center, Wayne State University, Detroit, 261 E Hancock St, Detroit, MI, 4820, USA.
Tracie R BakerDepartment of Pharmacology, Wayne State University, Detroit, 540 E. Canfield, Detroit, MI, 48201, USA.ORCID 0000-0002-5057-4155
Wayne State University · US

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI PAUL M STEMMER · 1985 to 2026
$68.4M
Pilot Project ProgramP30ES020957 · NIEHS · WAYNE STATE UNIVERSITY · PI RUNGE-MORRIS, MELISSA A · 2014 to 2021
$10.1M
Genetic and epigenetic mechanisms of infertility caused by endocrine disrupting chemicalsR01ES030722 · NIEHS · WAYNE STATE UNIVERSITY · PI BAKER, TRACIE R · 2020 to 2025
$2.1M
Adult and Transgenerational Toxicity Due to Developmental TCDD ExposureK01OD010462 · OD · WAYNE STATE UNIVERSITY · PI BAKER, TRACIE R · 2013 to 2017
$657k
Investigating the Developmental Mechanisms of TCDD-Induced Reproductive DysregulationF31ES030278 · NIEHS · WAYNE STATE UNIVERSITY · PI MEYER, DANIELLE · 2019 to 2021
$129k
NCI NIH HHS P30 CA022453NIEHS NIH HHS F31 ES030278NIEHS NIH HHS P30 ES020957NIEHS NIH HHS R01 ES030722NIH HHS K01 OD010462
6 · The paper itself

Abstract

The legacy endocrine disrupting chemical and aryl hydrocarbon receptor agonist, 2,3,7,8-tetrachlorodibenzo-

Indexed as

2,3,7,8-tetrachlorodibenzo-p-dioxinepigeneticsmethylationreproductiontransgenerationalzebrafish

Identifiers

PMID33214906
PMCPMC7660120
OpenAlexW3088666903

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.