Evidence map›Paper›PMID 33218007›Full record

ArticleMolecules (Basel, Switzerland)2020

Design and Synthesis of New Benzo[d]oxazole-Based Derivatives and Their Neuroprotective Effects on β-Amyloid-Induced PC12 Cells.

Zheng Liu, Ming Bian, Qian-Qian Ma, Zhuo Zhang, Huan-Huan Du, Cheng-Xi Wei

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zheng LiuMedicinal Chemistry and Pharmacology Institute, Inner Mongolia University for the Nationalities, Tongliao 028000, China.
Ming BianMedicinal Chemistry and Pharmacology Institute, Inner Mongolia University for the Nationalities, Tongliao 028000, China.
Qian-Qian MaMedicinal Chemistry and Pharmacology Institute, Inner Mongolia University for the Nationalities, Tongliao 028000, China.
Zhuo ZhangCollege of Pharmaceutical Sciences, Yanbian University, Yanji 133022, China.
Huan-Huan DuMedicinal Chemistry and Pharmacology Institute, Inner Mongolia University for the Nationalities, Tongliao 028000, China.
Cheng-Xi WeiMedicinal Chemistry and Pharmacology Institute, Inner Mongolia University for the Nationalities, Tongliao 028000, China.
Inner Mongolia University for Nationalities · CNYanbian University · CN

Funding

CAS "Light of West China" Program C.X. WeiInner Mongolia Natural Science Foundation 2008JQ01
6 · The paper itself

Abstract

A series of novel synthetic substituted benzo[d]oxazole-based derivatives (

Indexed as

Drug DesignAmyloid beta-PeptidesAmyloid Precursor Protein SecretasesAnimalsAspartic Acid Endopeptidasesbcl-2-Associated X ProteinBenzoxazolesCell SurvivalEnzyme ActivationGlycogen Synthase Kinase 3 betaHeart RateInflammationNeuroprotective AgentsNF-kappa BNitric Oxide Synthase Type IIPC12 CellsAger protein, ratAmyloid beta-PeptidesAmyloid Precursor Protein SecretasesAspartic Acid EndopeptidasesBace1 protein, ratbcl-2-Associated X ProteinBenzoxazolesGlycogen Synthase Kinase 3 betaNeuroprotective AgentsNF-kappa BNitric Oxide Synthase Type IIProto-Oncogene Proteins c-aktReceptor for Advanced Glycation End Productstau ProteinsAkt/GSK-3β/NF-κB signaling pathwayAlzheimer’s diseasebenzo[d]oxazolsynthesisthiadiazolesβ-amyloid

Identifiers

PMID33218007
PMCPMC7698601
OpenAlexW3106224281

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.