Evidence map›Paper›PMID 33219563›Full record

SynthesisAnnals of neurology2021

The Impact of SARS-CoV-2 on Stroke Epidemiology and Care: A Meta-Analysis.

Aristeidis H Katsanos, Lina Palaiodimou, Ramin Zand, Shadi Yaghi, Hooman Kamel, Babak B Navi, Guillaume Turc, Michele Romoli, Vijay K Sharma, Dimitris Mavridis and 9 more

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Annals of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Stroke network performance during the first COVID-19 pandemic stage: A meta-analysis based on stroke network models.International journal of stroke : official journal of the International Stroke Society · 2021
    Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Neurological complications caused by SARS-CoV-2.Clinical microbiology reviews · 2024
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Aristeidis H KatsanosDivision of Neurology, McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada.
Lina PalaiodimouSecond Department of Neurology, Attikon Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Ramin ZandNeuroscience Institute, Geisinger Health System, Danville, PA.ORCID 0000-0002-9477-0094
Shadi YaghiDepartment of Neurology, NYU Langone Health, New York, NY.ORCID 0000-0003-0031-1004
Hooman KamelClinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology, Weill Cornell Medicine, New York, NY.ORCID 0000-0002-5745-0307
Babak B NaviClinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology, Weill Cornell Medicine, New York, NY.ORCID 0000-0001-8424-6128
Guillaume TurcDepartment of Neurology, Paris Psychiatry and Neurosciences University Hospital Group, Sainte Anne Hospital, Paris, France.
Michele RomoliNeurology Unit, Maurizio Bufalini Hospital, Cesena, Italy.
Vijay K SharmaDivision of Neurology, Department of Medicine, National University Hospital, Singapore and School of Medicine, National University of Singapore, Singapore.
Dimitris MavridisDepartment of Primary Education, University of Ioannina, Ioannina, Greece.
Shima ShahjoueiNeuroscience Institute, Geisinger Health System, Danville, PA.
Luciana CataneseDivision of Neurology, McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada.
Ashkan ShoamaneshDivision of Neurology, McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada.ORCID 0000-0002-2802-1626
Konstantinos VadikoliasDepartment of Neurology, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
Konstantinos TsioufisFirst Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippokration Hospital, Athens, Greece.
Pagona LagiouDepartment of Hygiene, Epidemiology, and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Andrei V AlexandrovDepartment of Neurology, University of Tennessee Health Science Center, Memphis, TN.
Sotirios TsiodrasFourth Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Georgios TsivgoulisSecond Department of Neurology, Attikon Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-0640-3797

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEmerging data indicate an increased risk of cerebrovascular events with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and highlight the potential impact of coronavirus disease (COVID-19) on the management and outcomes of acute stroke. We conducted a systematic review and meta-analysis to evaluate the aforementioned considerations.

methodsWe performed a meta-analysis of observational cohort studies reporting on the occurrence and/or outcomes of patients with cerebrovascular events in association with their SARS-CoV-2 infection status. We used a random-effects model. Summary estimates were reported as odds ratios (ORs) and corresponding 95% confidence intervals (CIs).

resultsWe identified 18 cohort studies including 67,845 patients. Among patients with SARS-CoV-2, 1.3% (95% CI = 0.9-1.6%, I

interpretationSARS-CoV-2 appears to be associated with an increased risk of ischemic stroke, and potentially cryptogenic stroke in particular. It may also be related to an increased mortality risk. ANN NEUROL 2021;89:380-388.

Indexed as

Hospital MortalitySARS-CoV-2Case-Control StudiesComorbidityCOVID-19Diabetes MellitusHumansStrokeThrombectomyThrombolytic Therapy

Identifiers

PMID33219563
PMCPMC7753413

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.