Evidence mapPaperPMID 33224588Full record

ArticleAmerican journal of cardiovascular disease2020

Systemic microvascular dysfunction in COVID-19.

Leticia R Sabioni, Eduardo Tibirica, Cristiane C Lamas, Guilherme D Amorim, Andrea De Lorenzo

Open access · greenAbstract readCase Reports
In one paragraph

Article in American journal of cardiovascular disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Leticia R SabioniInstituto Nacional de Cardiologia Rio de Janeiro, Brazil.
Eduardo TibiricaInstituto Nacional de Cardiologia Rio de Janeiro, Brazil.
Cristiane C LamasInstituto Nacional de Cardiologia Rio de Janeiro, Brazil.
Guilherme D AmorimInstituto Nacional de Cardiologia Rio de Janeiro, Brazil.
Andrea De LorenzoInstituto Nacional de Cardiologia Rio de Janeiro, Brazil.
Instituto Nacional de Cardiologia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), while having lung injury as its most prominent feature, has been increasingly shown to affect endothelial cell function and the microvasculature. In this report, a woman with COVID-19, cardiac valve disease and spherocytosis was assessed with laser Doppler perfusion monitoring. Systemic microvascular reactivity was impaired during a worsening phase of COVID-19, but improved after clinical recovery; microcirculatory dysfunction paralleled systemic inflammation and pulmonary involvement. The assessment of systemic microcirculatory function may therefore provide insights on COVID-19 pathophysiology.

Indexed as

cardiac valve diseaseCOVID-19endothelial dysfunctionlaser Doppler perfusion imagingmicrovascular reactivity

Identifiers

PMID33224588
PMCPMC7675177
OpenAlexW3106649733

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.