Evidence map›Paper›PMID 33228049›Full record

ArticleInternational journal of molecular sciences2020

A Clearance Period after Soluble Lead Nanoparticle Inhalation Did Not Ameliorate the Negative Effects on Target Tissues Due to Decreased Immune Response.

Jana Dumková, Tereza Smutná, Lucie Vrlíková, Bohumil Dočekal, Daniela Kristeková, Zbyněk Večeřa, Zuzana Husáková, Veronika Jakešová, Adriena Jedličková, Pavel Mikuška and 8 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Subchronic Inhalation of TiOJournal of applied toxicology : JAT · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Jana DumkováDepartment of Histology and Embryology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0002-2834-6316
Tereza SmutnáDepartment of Histology and Embryology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
Lucie VrlíkováLaboratory of Molecular Morphogenesis, Institute of Animal Physiology and Genetics, v.v.i., Czech Academy of Sciences, 602 00 Brno, Czech Republic.
Bohumil DočekalDepartment of Environmental Analytical Chemistry, Institute of Analytical Chemistry, v.v.i., Czech Academy of Sciences, 602 00 Brno, Czech Republic.ORCID 0000-0002-1985-2807
Daniela KristekováLaboratory of Molecular Morphogenesis, Institute of Animal Physiology and Genetics, v.v.i., Czech Academy of Sciences, 602 00 Brno, Czech Republic.
Zbyněk VečeřaDepartment of Environmental Analytical Chemistry, Institute of Analytical Chemistry, v.v.i., Czech Academy of Sciences, 602 00 Brno, Czech Republic.
Zuzana HusákováDepartment of Chemistry, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.
Veronika JakešováLaboratory of Molecular Morphogenesis, Institute of Animal Physiology and Genetics, v.v.i., Czech Academy of Sciences, 602 00 Brno, Czech Republic.
Adriena JedličkováLaboratory of Molecular Morphogenesis, Institute of Animal Physiology and Genetics, v.v.i., Czech Academy of Sciences, 602 00 Brno, Czech Republic.
Pavel MikuškaDepartment of Environmental Analytical Chemistry, Institute of Analytical Chemistry, v.v.i., Czech Academy of Sciences, 602 00 Brno, Czech Republic.ORCID 0000-0001-7793-5929
Lukáš AlexaDepartment of Environmental Analytical Chemistry, Institute of Analytical Chemistry, v.v.i., Czech Academy of Sciences, 602 00 Brno, Czech Republic.ORCID 0000-0002-3637-3891
Pavel CoufalíkDepartment of Environmental Analytical Chemistry, Institute of Analytical Chemistry, v.v.i., Czech Academy of Sciences, 602 00 Brno, Czech Republic.
Michaela TvrdoňováDepartment of Chemistry, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0002-1686-4423
Kamil KřůmalDepartment of Environmental Analytical Chemistry, Institute of Analytical Chemistry, v.v.i., Czech Academy of Sciences, 602 00 Brno, Czech Republic.
Tomáš VaculovičDepartment of Chemistry, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.
Viktor KanickýDepartment of Chemistry, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0003-3136-1821
Aleš HamplDepartment of Histology and Embryology, Faculty of Medicine, Masaryk University, 625 00 Brno, Czech Republic.
Marcela BuchtováLaboratory of Molecular Morphogenesis, Institute of Animal Physiology and Genetics, v.v.i., Czech Academy of Sciences, 602 00 Brno, Czech Republic.ORCID 0000-0002-0262-6774
Czech Academy of Sciences · CZCzech Academy of Sciences, Institute of Analytical Chemistry · CZMasaryk University · CZ

Funding

Czech Science Foundation 20-02203S
6 · The paper itself

Abstract

The inhalation of metal (including lead) nanoparticles poses a real health issue to people and animals living in polluted and/or industrial areas. In this study, we exposed mice to lead(II) nitrate nanoparticles [Pb(NO

Indexed as

ActinsAdministration, InhalationAir PollutantsAnimalsBiological AvailabilityFemaleGene ExpressionHalf-LifeInhalation ExposureInterleukin-1alphaInterleukin-1betaInterleukin-6LeadLiverLungMacrophages, AlveolarActinsAir Pollutantsalpha-smooth muscle actin, mouseIl1a protein, mouseIL1B protein, mouseInterleukin-1alphaInterleukin-1betaInterleukin-6interleukin-6, mouseLeadlead nitrateNF-kappa BNitratesTgfb1 protein, mouseTransforming Growth Factor beta1Tumor Necrosis Factor-alphaclearanceinhalationLA-ICP-MS imaginglead nanoparticlestoxicity

Identifiers

PMID33228049
PMCPMC7699374
OpenAlexW3106377133

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.