ArticleIndian journal of ophthalmology2020
Photorefractive keratectomy (PRK) Prediction, Examination, tReatment, Follow-up, Evaluation, Chronic Treatment (PERFECT) protocol - A new algorithmic approach for managing post PRK haze.
Article in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Seasonal Effects on Corneal Densitometry and Haze After Mitomycin C-Assisted Photorefractive Keratectomy.Journal of clinical medicine · 2026Article
- Management of Corneal Haze After Photorefractive Keratectomy.Ophthalmology and therapy · 2023Review
- Vitamin D and eye: Current evidence and practice guidelines.Indian journal of ophthalmology · 2023Review
- Article
- Commentary: Precision - The hallmark of refractive surgery.Indian journal of ophthalmology · 2023Article
- Corneal stromal repair and regeneration.Progress in retinal and eye research · 2022Review
- Biochemical and molecular alterations and potential clinical applications of biomarkers in keratoconus.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to discuss the possible risk factors predisposing to post photorefractive keratectomy (PRK) haze formation and develop and validate a risk scoring system, so that this could be applied to our clinical practice as an algorithmic approach.
methodsStudy was divided into 2 arms, in the retrospective arm we looked at 238 eyes of patients undergoing PRK where certain presumed risk factors from literature and clinical experience were identified and statistical significance of association was studied in the development of corneal haze. The risk scoring system was applied to the 450 eyes in the prospective arm for validation. This was then used to formulate an algorithmic approach to manage post-PRK haze.
results22 out of 238 eyes in the retrospective arm developed haze where risk factors such as contact lens intolerance, altered tear film break up time, meibomian gland drop out and vitamin d levels were significantly associated with post-PRK haze (p < 0.05) and these factors were identified in the prospective arm. Treatment of these modifiable factors led to a significant reduction in post-PRK haze.
conclusionThus identifying and treating risk factors of haze in patients undergoing PRK could improve surgical outcomes and patient satisfaction.
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Registered trials
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