Evidence map›Paper›PMID 33233316›Full record

ArticleVaccines2020

Anti-Tick Microbiota Vaccine Impacts

Lourdes Mateos-Hernández, Dasiel Obregón, Jennifer Maye, Jeremie Borneres, Nicolas Versille, José de la Fuente, Agustín Estrada-Peña, Adnan Hodžić, Ladislav Šimo, Alejandro Cabezas-Cruz

Abstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Review
  2. Article
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  4. bioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Article
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  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Frontiers in microbiology · 2025
    Article
  18. Microbial community variations in adultFrontiers in microbiology · 2025
    Article
  19. Exploring the relationship betweenComputational and structural biotechnology journal · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lourdes Mateos-HernándezUMR BIPAR, INRAE, ANSES, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est, Marie Curie, 94706 Maisons-Alfort, France.ORCID 0000-0001-9566-7710
Dasiel ObregónSchool of Environmental Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0002-5786-1114
Jennifer MayeSEPPIC Paris La Défense, 92250 La Garenne Colombes, France.
Jeremie BorneresSEPPIC Paris La Défense, 92250 La Garenne Colombes, France.
Nicolas VersilleSEPPIC Paris La Défense, 92250 La Garenne Colombes, France.
José de la FuenteSaBio, Instituto de Investigación en Recursos Cinegéticos (IREC-CSIC-UCLM-JCCM), 13005 Ciudad Real, Spain.ORCID 0000-0001-7383-9649
Agustín Estrada-PeñaFaculty of Veterinary Medicine, University of Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0001-7483-046X
Adnan HodžićInstitute of Parasitology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna 1210, Austria.
Ladislav ŠimoUMR BIPAR, INRAE, ANSES, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est, Marie Curie, 94706 Maisons-Alfort, France.ORCID 0000-0002-4472-1016
Alejandro Cabezas-CruzUMR BIPAR, INRAE, ANSES, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est, Marie Curie, 94706 Maisons-Alfort, France.ORCID 0000-0002-8660-730X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tick microbiota is a highly complex ensemble of interacting microorganisms. Keystone taxa, with a central role in the microbial networks, support the stability and fitness of the microbial communities. The keystoneness of taxa in the tick microbiota can be inferred from microbial co-occurrence networks. Microbes with high centrality indexes are highly connected with other taxa of the microbiota and are expected to provide important resources to the microbial community and/or the tick. We reasoned that disturbance of vector microbiota by removal of ubiquitous and abundant keystone bacteria may disrupt the tick-microbiota homeostasis causing harm to the tick host. These observations and reasoning prompted us to test the hypothesis that antibodies targeting keystone bacteria may harm the ticks during feeding on immunized hosts. To this aim, in silico analyses were conducted to identify keystone bacteria in the microbiota of

Indexed as

anti-tick microbiota vaccinestick controlα-Gal

Identifiers

PMID33233316
PMCPMC7711837

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.