Evidence mapPaperPMID 33233321Full record

ReviewJournal of clinical medicine2020

Predictors and Biomarkers of Subclinical Leaflet Thrombosis after Transcatheter Aortic Valve Implantation.

Katarzyna Pieniak, Szymon Jędrzejczyk, Olaf Domaszk, Kajetan Grodecki, Bartosz Rymuza, Zenon Huczek, Janusz Kochman, Krzysztof J Filipiak, Aleksandra Gąsecka

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Prediction model for leaflet thrombosis in patients undergoing transcatheter aortic valve implantation: the EFFORT study.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Observational
  3. Thrombus characterisation and evolution of hypoattenuating leaflet thickening after transcatheter aortic valve implantation.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Circulating Monocyte Subsets and Transcatheter Aortic Valve Replacement.International journal of molecular sciences · 2022
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Katarzyna PieniakDepartment of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0003-3915-5758
Szymon JędrzejczykDepartment of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0003-4674-0736
Olaf DomaszkDepartment of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Kajetan GrodeckiDepartment of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-0358-5679
Bartosz RymuzaDepartment of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Zenon HuczekDepartment of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Janusz KochmanDepartment of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Krzysztof J FilipiakDepartment of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-6563-0877
Aleksandra GąseckaDepartment of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0001-5083-7587
Medical University of Warsaw · PL

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego DI2017004047Narodowe Centrum Nauki PRELUDIUM 2018/31/N/NZ7/02260
6 · The paper itself

Abstract

Transcatheter aortic valve implantation (TAVI) is a recent revolutionary treatment for high-risk patients with severe aortic stenosis who are not suitable for surgery, expanding to intermediate and low-risk patients. Valve leaflet thrombosis (LT) is a potentially fatal complication after TAVI. The incidence of subclinical LT is as high as 25% among patients in the first year after TAVI. Subclinical LT may evolve into symptomatic thrombosis or lead to premature bioprosthesis degeneration, increasing the risk of neurological complications. Because imaging-based methods have limited sensitivity to detect subclinical LT, there is an urgent need for predictors and biomarkers that would make it possible to predict LT after TAVI. Here, we summarize recent data regarding (i) patient-related, (ii) procedure-related, (iii) blood-based and (iv) imaging predictors and biomarkers which might be useful for the early diagnosis of subclinical LT after TAVI. Prevention of LT might offer an opportunity to improve risk stratification and tailor therapy after TAVI.

Indexed as

aortic stenosisbiomarkersleaflet thrombosispredictorsTAVI

Identifiers

PMID33233321
PMCPMC7700436
OpenAlexW3099739991

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.