Evidence map›Paper›PMID 33233364›Full record

ArticleInternational journal of environmental research and public health2020

Decompressive Craniectomy Improves QTc Interval in Traumatic Brain Injury Patients.

Wojciech Dabrowski, Dorota Siwicka-Gieroba, Chiara Robba, Rafael Badenes, Katarzyna Kotfis, Todd T Schlegel, Andrzej Jaroszynski

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Wojciech DabrowskiDepartment of Anaesthesiology and Intensive Care, Medical University of Lublin, 20-954 Lublin, Poland.ORCID 0000-0003-0449-2375
Dorota Siwicka-GierobaDepartment of Anaesthesiology and Intensive Care, Medical University of Lublin, 20-954 Lublin, Poland.ORCID 0000-0002-1001-0080
Chiara RobbaDepartment of Anaesthesia and Intensive Care, Policlinico San Martino, 1100 Genova, Italy.
Rafael BadenesDepartment of Anaesthesiology and Intensive Care, Hospital Clìnico Universitario de Valencia, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0001-7017-0150
Katarzyna KotfisDepartment Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-8430-1369
Todd T SchlegelDepartment of Molecular Medicine and Surgery, Karolinska Institute, SE-171 76 Stockholm, Sweden.ORCID 0000-0003-1997-3227
Andrzej JaroszynskiDepartment of Nephrology, Collegium Medicum, Jan Kochanowski University of Kielce, 25-736 Kielce, Poland.
Medical University of Lublin · PLJan Kochanowski University · PLKarolinska Institutet · SEOspedale Policlinico San Martino · ITPomeranian Medical University · PLUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraumatic brain injury (TBI) is commonly associated with cardiac dysfunction, which may be reflected by abnormal electrocardiograms (ECG) and/or contractility. TBI-related cardiac disorders depend on the type of cerebral injury, the region of brain damage and the severity of the intracranial hypertension. Decompressive craniectomy (DC) is commonly used to reduce intra-cranial hypertension (ICH). Although DC decreases ICH rapidly, its effect on ECG has not been systematically studied. The aim of this study was to analyze the changes in ECG in patients undergoing DC.

methodsAdult patients without previously known cardiac diseases treated for isolated TBI with DC were studied. ECG variables, such as: spatial QRS-T angle (spQRS-T), corrected QT interval (QTc), QRS and T axes (QRS

results48 patients (17 female and 31 male) aged 18-64 were studied. Intra-cranial pressure correlated with QTc before DC (

conclusionsICP positively correlates with QTc interval in patients with isolated TBI, and DC for relief of ICH reduces QTc and spQRS-T. However, DC might also increase risk for life-threatening cardiac arrhythmias, especially in ICH patients with notably prolonged QTc before and increased iCEB after DC.

Indexed as

AdolescentAdultArrhythmias, CardiacBrain Injuries, TraumaticDecompressive CraniectomyElectrocardiographyFemaleHumansIntracranial HypertensionIntracranial PressureMaleMiddle AgedTreatment OutcomeYoung Adultcardiac arrhythmiascardiac disorderselectrocardiographythe index of cardio-electrophysiological balancetraumatic brain injury

Identifiers

PMID33233364
PMCPMC7700327
OpenAlexW3109038052

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.