ReviewMolecules (Basel, Switzerland)2020
Intestinal Anti-Inflammatory Activity of Terpenes in Experimental Models (2010-2020): A Review.
Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- The therapeutic potential of terpenes in periodontal disease: a systematic review of pre-clinical animal studies.Inflammopharmacology · 2025Pooled it
- Medicinal Plants and Their Impact on the Gut Microbiome in Mental Health: A Systematic Review.Nutrients · 2022Pooled it
- [Methyl syringate alleviates DSS-induced colitis in mice by suppressing intestinal epithelial cell apoptosisNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- Characterization of Heterotrigona itama Propolis Extracts: Phytochemicals and Thermal Insights.Chemistry & biodiversity · 2026Article
- Toxoplasma gondii disrupts intestinal microbiota and host metabolism in a rat model.PLoS neglected tropical diseases · 2025Article
- Bioactive Potential of Terpenes from Mediterranean Scrub Plants: A Review.Molecules (Basel, Switzerland) · 2025Review
- Anti-Inflammatory Activity of Thymol and Thymol-Rich Essential Oils: Mechanisms, Applications, and Recent Findings.Molecules (Basel, Switzerland) · 2025Review
- Effect of Oregano Essential Oil on Growth and Composition of Gut Prokaryote Microbiota on Striped Bass (Microorganisms · 2025Article
- An observational feasibility study on the impact of green exposure on major depressive episode symptomatology and inflammatory biomarkers.Frontiers in psychiatry · 2025Article
- Targeting microglia polarization with Chinese herb-derived natural compounds for neuroprotection in ischemic stroke.Frontiers in cell and developmental biology · 2025Review
- Essential Oils as Alternative Green Broad-Spectrum Biocides.Plants (Basel, Switzerland) · 2024Review
- The gut microbiome of Baka forager-horticulturalists from Cameroon is optimized for wild plant foods.iScience · 2024Article
- Limonene Exerts Anti-Inflammatory Effect on LPS-Induced Jejunal Injury in Mice by Inhibiting NF-κB/AP-1 Pathway.Biomolecules · 2024Article
- TRAIL-Sensitizing Effects of Flavonoids in Cancer.International journal of molecular sciences · 2023Review
- Therapeutic Potential of Myrtenal and Its Derivatives-A Review.Life (Basel, Switzerland) · 2023Review
- Antispasmodic Effect ofPharmaceutics · 2023Article
- Terpenes: Modulating anti-inflammatory signaling in inflammatory bowel disease.Pharmacology & therapeutics · 2023Review
- Glycosides as Potential Medicinal Components for Ulcerative Colitis: A Review.Molecules (Basel, Switzerland) · 2023Review
- Anti-Inflammatory and Cytotoxic Activities of Clerodane-Type Diterpenes.Molecules (Basel, Switzerland) · 2023Review
- Carvacrol-A Natural Phenolic Compound with Antimicrobial Properties.Antibiotics (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammatory bowel diseases (IBDs) refer to a group of disorders characterized by inflammation in the mucosa of the gastrointestinal tract, which mainly comprises Crohn's disease (CD) and ulcerative colitis (UC). IBDs are characterized by inflammation of the intestinal mucosa, are highly debilitating, and are without a definitive cure. Their pathogenesis has not yet been fully elucidated; however, it is assumed that genetic, immunological, and environmental factors are involved. People affected by IBDs have relapses, and therapeutic regimens are not always able to keep symptoms in remission over the long term. Natural products emerge as an alternative for the development of new drugs; bioactive compounds are promising in the treatment of several disorders, among them those that affect the gastrointestinal tract, due to their wide structural diversity and biological activities. This review compiles 12 terpenes with intestinal anti-inflammatory activity evaluated in animal models and in vitro studies. The therapeutic approach to IBDs using terpenes acts basically to prevent oxidative stress, combat dysbiosis, restore intestinal permeability, and improve the inflammation process in different signaling pathways.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.