ArticleScientific reports2020
Bioassay-based Corchorus capsularis L. leaf-derived β-sitosterol exerts antileishmanial effects against Leishmania donovani by targeting trypanothione reductase.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- Article
- Natural product-based therapeutic strategies againstFrontiers in microbiology · 2026Review
- Review
- Anticoccidial activity of the secondary metabolites in alpine plants frequently ingested by wild Japanese rock ptarmigans.International journal for parasitology. Parasites and wildlife · 2024Article
- Averrhoa carambola Leaf Extract Induces Apoptosis-Like Death with Increased ROS Generation in Leishmania donovani.Acta parasitologica · 2024Article
- The Potential Use of Peptides in the Fight against Chagas Disease and Leishmaniasis.Pharmaceutics · 2024Review
- Recent Advances in Chemotherapeutics for Leishmaniasis: Importance of the Cellular Biochemistry of the Parasite and Its Molecular Interaction with the Host.Pathogens (Basel, Switzerland) · 2023Review
- Antileishmanial and Antiplasmodial Activities of Secondary Metabolites from the Root ofMolecules (Basel, Switzerland) · 2023Article
- Antileishmanial Activity and In Silico Molecular Docking Studies ofTropical medicine and infectious disease · 2023Article
- Therapeutic efficacy of β-sitosterol treatment onFrontiers in microbiology · 2023Article
- Human Lung Cancer (A549) Cell Line Cytotoxicity and Anti-Pharmaceuticals (Basel, Switzerland) · 2022Article
- An Overview of GenusPlants (Basel, Switzerland) · 2022Review
- Metabolic Pathways ofPharmaceutics · 2022Review
- A Comprehensive Review ofAntioxidants (Basel, Switzerland) · 2022Review
- Effects of a Serine Protease Inhibitor N-Pharmaceutics · 2022Article
- Sesamol Induces Apoptosis-Like Cell Death inFrontiers in cellular and infection microbiology · 2021Article
- Anti-leishmanial effect of the hydroalcoholic extract of the leaves, roots and seeds ofAvicenna journal of phytomedicineArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leishmaniasis, a major neglected tropical disease, affects millions of individuals worldwide. Among the various clinical forms, visceral leishmaniasis (VL) is the deadliest. Current antileishmanial drugs exhibit toxicity- and resistance-related issues. Therefore, advanced chemotherapeutic alternatives are in demand, and currently, plant sources are considered preferable choices. Our previous report has shown that the chloroform extract of Corchorus capsularis L. leaves exhibits a significant effect against Leishmania donovani promastigotes. In the current study, bioassay-guided fractionation results for Corchorus capsularis L. leaf-derived β-sitosterol (β-sitosterol
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Registered trials
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