Evidence map›Paper›PMID 33237355›Full record

Trial reportInternational urogynecology journal2021

A model identifying characteristics predictive of successful pelvic floor muscle training outcomes among women with stress urinary incontinence.

Kaylee C L Brooks, Kevin Varette, Marie-Andrée Harvey, Magali Robert, Robert J Brison, Andrew Day, Kevin Baker, Vincent Della Zazzera, Eric Sauerbrei, Linda McLean

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in International urogynecology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01602107 (Optimizing Treatment Outcomes for Women With Stress Urinary Incontinence Through the Identification of Factors Contributing to Successful Interventions), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01602107 nacompletednot on this map

Optimizing Treatment Outcomes for Women With Stress Urinary Incontinence Through the Identification of Factors Contributing to Successful Interventions

TypeinterventionalSponsorQueen's UniversityRan2011 to 2017Enrolled176ConditionsStress Urinary IncontinenceArmsPelvic Floor muscle strengthening exercises
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kaylee C L BrooksSchool of Rehabilitation Sciences, University of Ottawa, Rm E260C, Building E, 200 Lees Avenue, Ottawa, ON, K1N 6N5, Canada.
Kevin VaretteSchool of Rehabilitation Therapy, Queen's University, Kingston, Canada.
Marie-Andrée HarveyDepartment of Obstetrics and Gynaecology, Kingston General Hospital, Kingston, Canada.
Magali RobertDepartment of Obstetrics and Gynaecology, Foothills General Hospital, Calgary, Canada.
Robert J BrisonDepartment of Emergency Medicine, Kingston General Hospital, Kingston, Canada.
Andrew DayDepartment of Population Health Sciences, Queen's University, Kingston, Canada.
Kevin BakerDepartment of Obstetrics and Gynaecology, The Ottawa Hospital, Ottawa, Canada.
Vincent Della ZazzeraDepartment of Obstetrics and Gynaecology, Hôpital Montfort, Ottawa, Canada.
Eric SauerbreiDepartment of Radiology, Kingston General Hospital, Kingston, Canada.
Linda McLeanSchool of Rehabilitation Sciences, University of Ottawa, Rm E260C, Building E, 200 Lees Avenue, Ottawa, ON, K1N 6N5, Canada. linda.mclean@uottawa.ca.ORCID http://orcid.org/0000-0003-0343-5168

Funding

CIHR 111168
6 · The paper itself

Abstract

introduction and hypothesisThe aim of this study was to prospectively identify aspects of baseline demographic, clinical, and pelvic morphology of women with stress urinary incontinence (SUI) that are predictive of cure with physiotherapist-supervised pelvic floor muscle training (PFMT).

methodsWomen ≥18 years old with SUI were recruited from urogynecology and pelvic health physiotherapy clinics. Participants completed a 3-day bladder diary, the International Consultation on Incontinence Questionnaire Urinary Incontinence Short Form (ICIQ-UI-SF), a standardized pad test, manual assessment of pelvic floor muscle (PFM) strength and tone, and transperineal ultrasound (TPUS) assessment of their urogenital structures at rest while in a supine position and standing, and during contraction, straining, and coughing. Participants attended six physiotherapy sessions over 12 weeks and performed a home PFMT program. The assessment was repeated after the intervention; cure was defined as a dry (≤2 g) pad test.

resultsSeventy-seven women aged 50 (±10) years completed the protocol; 38 (49%) were deemed cured. Based on univariate testing, four predictors were entered into a binary logistic regression model: ICIQ-UI-SF, PFM tone, bladder neck (BN) height in a quiet standing position, and BN height during a cough in a standing position. The model was significant (p < 0.001), accurately classifying outcome in 74% of participants. The model, validated through bootstrapping, performed moderately, with the area under the receiver operating characteristic curve = 0.80 (95% CI: 0.69-0.90; p = 0.00), and with 70% sensitivity and 75% specificity.

conclusionsWomen with better bladder support in a standing position and less severe symptoms were most likely to be cured with PFMT. CLINICAL

trial registration#NCT01602107.

Indexed as

Urinary IncontinenceUrinary Incontinence, StressAdolescentExercise TherapyFemaleHumansPelvic FloorTreatment OutcomeUrinary BladderPelvic floor musclesPelvic floor muscle trainingPhysiotherapyPredictive modelStress urinary incontinenceTransperineal ultrasound

Identifiers

PMID33237355
PMCPMC7902568

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.