Evidence map›Paper›PMID 33239901›Full record

ArticleInternational journal of nephrology and renovascular disease2020

Correlation Between Parathyroid Hormone Levels with Urinary Magnesium Excretion in Patients with Non-Dialysis Dependent Chronic Kidney Disease.

Raimunda Sheyla Carneiro Dias, Dyego José de Araújo Brito, Elisângela Milhomem Dos Santos, Rayanna Cadilhe de Oliveira Costa, Andrea Martins Melo Fontenele, Elane Viana Hortegal Furtado, Joyce Santos Lages, Alcione Miranda Dos Santos, Elton Jonh Freitas Santos, Érika Cristina Ribeiro de Lima Carneiro and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nephrology and renovascular disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Magnesium-A More Important Role in CKD-MBD than We Thought.Diagnostics (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Raimunda Sheyla Carneiro DiasCenter for Prevention of Kidney Diseases, University Hospital of the Federal University of Maranhão, São Luís, MA, Brazil.ORCID 0000-0003-1851-9495
Dyego José de Araújo BritoCenter for Prevention of Kidney Diseases, University Hospital of the Federal University of Maranhão, São Luís, MA, Brazil.
Elisângela Milhomem Dos SantosNursing Department, Federal University of Maranhão, São Luís, MA, Brazil.ORCID 0000-0001-9690-5311
Rayanna Cadilhe de Oliveira CostaCenter for Prevention of Kidney Diseases, University Hospital of the Federal University of Maranhão, São Luís, MA, Brazil.ORCID 0000-0001-9124-9968
Andrea Martins Melo FonteneleCenter for Prevention of Kidney Diseases, University Hospital of the Federal University of Maranhão, São Luís, MA, Brazil.ORCID 0000-0002-0617-8403
Elane Viana Hortegal FurtadoCenter for Prevention of Kidney Diseases, University Hospital of the Federal University of Maranhão, São Luís, MA, Brazil.
Joyce Santos LagesCenter for Prevention of Kidney Diseases, University Hospital of the Federal University of Maranhão, São Luís, MA, Brazil.
Alcione Miranda Dos SantosPublic Health Department, Federal University of Maranhão, São Luís, MA, Brazil.ORCID 0000-0001-9711-0182
Elton Jonh Freitas SantosCenter for Prevention of Kidney Diseases, University Hospital of the Federal University of Maranhão, São Luís, MA, Brazil.ORCID 0000-0002-1743-9103
Érika Cristina Ribeiro de Lima CarneiroCenter for Prevention of Kidney Diseases, University Hospital of the Federal University of Maranhão, São Luís, MA, Brazil.
Maria Célia Cruz DinizCenter for Prevention of Kidney Diseases, University Hospital of the Federal University of Maranhão, São Luís, MA, Brazil.ORCID 0000-0002-0012-3401
Carla Déa Trindade BarbosaCenter for Prevention of Kidney Diseases, University Hospital of the Federal University of Maranhão, São Luís, MA, Brazil.ORCID 0000-0001-5974-7502
Alessandra Costa de Sales MunizCenter for Prevention of Kidney Diseases, University Hospital of the Federal University of Maranhão, São Luís, MA, Brazil.ORCID 0000-0003-0317-5116
Ana Karina Teixeira da Cunha FrançaPublic Health Department, Federal University of Maranhão, São Luís, MA, Brazil.ORCID 0000-0002-4460-2631
Natalino Salgado FilhoDepartment of Medicine I, Federal University of Maranhão, São Luís, MA, Brazil.ORCID 0000-0003-4105-2010
Denizar Vianna AraújoDepartment of Internal Medicine, University of the State of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID 0000-0003-3281-671X
Mário Bernardo-FilhoLaboratory of Mechanical Vibrations and Integrative Practices, Department of Biophysics and Biometrics, Institute of Biology Roberto Alcântara Gomes and Polyclinic Américo Piquet Carneiro, University of the State of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID 0000-0002-4718-448X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDisorders of mineral metabolism occur in most patients with chronic kidney disease (CKD). The aim of this work was to correlate parathyroid hormone (PTH) levels with urinary magnesium excretion in patients with non-dialysis dependent CKD.

methodsCross-sectional study. Concentrations of creatinine, magnesium, calcium, phosphate, parathyroid hormone (PTH), 25-hydroxyvitamin D [25(OH)D] and alkaline phosphatase (ALP) were determined in blood samples. The assessment of urinary magnesium levels was performed by means of total daily excretion and by the excretion fraction (FEMg).

resultsThe study evaluated 163 patients with a mean age of 60.7 ± 11.7 years and 51.0% were male. In the highest quartile of PTH (>89.5pg/mL), the mean levels of FEMg and ALP were higher (p<0.05). In the unadjusted regression analysis, the following variables were related to serum PTH levels: FEMg (odds ratio (OR) = 1.12; 95% confidence intervals (CI): 1.02-1.23), calcium (OR = 0.45; 95% CI: 0.22-0.90), ALP (OR = 1.02; 95% CI: 1.00-1.03) and eGFR (OR = 0.92; 95% CI: 1.00-1.03). After an adjusted analysis, only one FEMg and ALP will remain correlated with PTH.

conclusionIn patients with non-dialysis dependent CKD, FEMg and ALP were some variables that remained associated with PTH.

Indexed as

kidney diseasesmagnesiumparathyroid hormone

Identifiers

PMID33239901
PMCPMC7682596

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.