Evidence map›Paper›PMID 33240391›Full record

ArticleTherapeutic advances in gastroenterology2020

Randomized controlled study on the effects of triple therapy including vonoprazan or rabeprazole for the second-line treatment of

Mariko Hojo, Daisuke Asaoka, Tsutomu Takeda, Yuji Shimada, Kenshi Matsumoto, Kohei Matsumoto, Noboru Yatagai, Yoichi Akazawa, Kumiko Ueda, Hiroya Ueyama and 1 more

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Treatment ofWorld journal of gastroenterology · 2024
    Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Review
  8. Article
  9. Vonoprazan and proton pump inhibitors: Which is superior forWorld journal of gastroenterology · 2025
    Article
  10. Article
  11. The efficacy and safety of Vonoprazan and Tegoprazan inTherapeutic advances in gastroenterology · 2025
    Article
  12. Newer Therapies for RefractoryAntibiotics (Basel, Switzerland) · 2024
    Review
  13. P-CABTherapeutic advances in gastroenterology · 2024
    Article
  14. Review
  15. Antibiotic Resistance, Susceptibility Testing and Stewardship inInternational journal of molecular sciences · 2023
    Review
  16. Seven-day vonoprazan-based triple therapy as first-lineJGH open : an open access journal of gastroenterology and hepatology · 2023
    Article
  17. Update on the second-line treatment ofTherapeutic advances in gastroenterology · 2023
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Mariko HojoDepartment of Gastroenterology, Juntendo University School of Medicine, 2-1-1Hongo Bunkyo-ku, Tokyo, 113-8421, Japan.ORCID https://orcid.org/0000-0001-9671-5585
Daisuke AsaokaDepartment of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
Tsutomu TakedaDepartment of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
Yuji ShimadaDepartment of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
Kenshi MatsumotoDepartment of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
Kohei MatsumotoDepartment of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
Noboru YatagaiDepartment of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
Yoichi AkazawaDepartment of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
Kumiko UedaDepartment of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
Hiroya UeyamaDepartment of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
Akihito NagaharaDepartment of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
Juntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimInhibition of gastric acid secretion is important for eradicating

methodsEligible patients with

resultsIn total, 46 and 41 patients were analyzed as intention to treat (ITT) and per protocol (PP), respectively. Eradication rates in the VPZ and RPZ groups were 73.9% [95% confidence interval (CI) 51.6-89.8%] and 82.6% (95% CI 61.2-95.0%) based on ITT analysis, respectively (

conclusionThere were no significant differences in efficacy and safety between second-line therapies including VPZ or RPZ.

Indexed as

Helicobacter pyloripotassium-competitive acid blockerrabeprazolesecond-line treatmentvonoprazan

Identifiers

PMID33240391
PMCPMC7675913
OpenAlexW3104003040

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.