Evidence map›Paper›PMID 33247228›Full record

ArticleScientific reports2020

Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers.

Vladimír Kincl, Roman Panovský, Martin Pešl, Jan Máchal, Lenka Juříková, Jana Haberlová, Lucia Masárová

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Myocardial native TOrphanet journal of rare diseases · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Vladimír KinclDepartment of Internal Medicine/Cardiology, Faculty of Medicine, St. Anne's University Hospital, Masaryk University, Brno, Czech Republic. vladimir.kincl@fnusa.cz.
Roman PanovskýDepartment of Internal Medicine/Cardiology, Faculty of Medicine, St. Anne's University Hospital, Masaryk University, Brno, Czech Republic.
Martin PešlDepartment of Internal Medicine/Cardiology, Faculty of Medicine, St. Anne's University Hospital, Masaryk University, Brno, Czech Republic.
Jan MáchalInternational Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
Lenka JuříkováDepartment of Pediatric Neurology, Faculty of Medicine, University Hospital Brno, Masaryk University, Brno, Czech Republic.
Jana HaberlováDepartment of Pediatric Neurology, Second Faculty of Medicine, University Hospital Motol, Charles University, Prague, Czech Republic.
Lucia MasárováDepartment of Internal Medicine/Cardiology, Faculty of Medicine, St. Anne's University Hospital, Masaryk University, Brno, Czech Republic.
St. Anne's University Hospital Brno · CZMasaryk University · CZCharles University · CZUniversity Hospital Brno · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess subclinical cardiac function impairment in Duchenne dystrophy (DMD) female carriers. Forty-four female subjects proved as DMD carriers underwent echocardiographic examination including tissue Doppler imaging (TDI) of mitral and tricuspid annulus. Seventeen age-matched healthy female subjects served as controls. A significant differences in peak systolic annular velocity (Sa) between carriers and controls were found for lateral and septal part of the mitral annulus and for tricuspid annulus (0.09 vs. 0.11 m/s, p < 0.001, 0.08 vs. 0.09 m/s, p < 0.01 and 0.13 vs. 0.14 m/s, p = 0.02 respectively). There was also difference in early diastolic velocity (Ea) of the septal part of the mitral annulus (0.11 vs. 0.13 m/s, p = 0.03). The subclinical deterioration of systolic function is presented even in asymptomatic DMD female carriers.

Indexed as

HeterozygoteAdultBlood Flow VelocityCase-Control StudiesEchocardiography, DopplerFemaleHumansMiddle AgedMitral ValveMuscular Dystrophy, DuchenneSystoleTricuspid ValveVentricular Dysfunction, Left

Identifiers

PMID33247228
PMCPMC7695725
OpenAlexW3106932175

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.