Evidence map›Paper›PMID 33248407›Full record

ArticleBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2021

The impact of Sample Handling Time on metformin serum concentration.

Edyta Sutkowska, Paulina Fortuna, Bernadetta Kałuża, Karolina Sutkowska, Paweł Hodurek, Mariusz G Fleszar

2 registry-linked trialsOpen access · goldAbstract read
PubMed Publisher
In one paragraph

Article in Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT03398356. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03398356 phase4completed

The Assessment of the Effect of Metformin and Its Serum Concentration on the Concentration of Substances Associated With the Production of Nitric Oxide in Patients With Impaired Carbohydrate Metabolism

Ran2017Enrolled47Registered outcomes6Posted comparisons0ConditionsImpaired Fasting Glucose (IFG), Impaired Glucose Tolerance (IGT), PrediabetesArmsMetformin
PMID 9742977PMID 15606381PMID 34062418PMID 16802130PMID 16759299PMID 21186243PMID 34083618PMID 28436051other papers from this trial
Open the trial in the graph
NCT03426566 completednot on this map

Prevention of Foot Injuries - Abnormal Distribution Patterns of Plantar Pressure in Patients With Diabetes and Its Connection to Peripheral Neuropathy, Gender, Age and BMI

TypeobservationalSponsorWroclaw Medical UniversityRan2012 to 2014Enrolled974ConditionsDiabetes ComplicationsArmsretrospective observational study with no intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Edyta SutkowskaDepartment and Division of Medical Rehabilitation, Wroclaw Medical University, Poland. Electronic address: edyta.sutkowska@umed.wroc.pl.
Paulina FortunaDepartment of Medical Biochemistry, Wroclaw Medical University, Poland. Electronic address: paulina.fortuna@umed.wroc.pl.
Bernadetta KałużaDepartment of Internal Medicine, Endocrinology and Diabetology, Central Clinical Hospital of the Ministry of the Interior, Warsaw, Poland. Electronic address: bernadettta@o2.pl.
Karolina SutkowskaFaculty of Medicine, Wroclaw Medical University, Poland. Electronic address: karolina.sutkowska@student.umed.wroc.pl.
Paweł HodurekDepartment of Medical Biochemistry, Wroclaw Medical University, Poland. Electronic address: pawel.hodurek@umed.wroc.pl.
Mariusz G FleszarDepartment of Medical Biochemistry, Wroclaw Medical University, Poland; Łukasiewicz Research Network, PORT Polish Center for Technology Development, Poland. Electronic address: mariusz.fleszar@umed.wroc.pl.
Wroclaw Medical University · PLCentral Clinical Hospital · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is an informative article which can help research providers to arrange and conduct studies dedicated to the assessment of metformin serum concentrations. If there is a problem with coordination of sample preparation and it is necessary to measure metformin concentration, two hours gap between blood drain and centrifugation has no impact on the results.

Indexed as

Blood Specimen CollectionDrug MonitoringCentrifugationChromatography, LiquidDiabetes Mellitus, Type 2HumansHypoglycemic AgentsMass SpectrometryMetforminProof of Concept StudyReproducibility of ResultsTime FactorsWorkflowHypoglycemic AgentsMetforminCentrifugationMetformin serum concentrationSample Handling Time

Identifiers

PMID33248407
OpenAlexW3107665067

What Socratic holds

Texttitle and abstract
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.