Evidence map›Paper›PMID 33249335›Full record

ReviewJournal of reproductive immunology2021

Maternal immune responses and obstetrical outcomes of pregnant women with COVID-19 and possible health risks of offspring.

Marcelo Borges Cavalcante, Candice Torres de Melo Bezerra Cavalcante, Manoel Sarno, Ricardo Barini, Joanne Kwak-Kim

Open access · greenAbstract readReview
In one paragraph

Review in Journal of reproductive immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 64 citations in OpenAlex.

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  15. Cytokine Imbalance as a Biomarker of Treatment-Resistant Schizophrenia.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Marcelo Borges CavalcanteDepartment of Obstetrics and Gynecology, Fortaleza University (UNIFOR), Fortaleza, CE, 60.811-905, Brazil; CONCEPTUS - Reproductive Medicine, Fortaleza, CE, 60.170-240, Brazil. Electronic address: marcelocavalcante.med@gmail.com.
Candice Torres de Melo Bezerra CavalcanteDepartment of Pediatrics, Fortaleza University (UNIFOR), Fortaleza, CE, 60.811-905, Brazil.
Manoel SarnoDepartment of Obstetrics and Gynecology, Federal University of Bahia (UFBA), Salvador, BA, 40.026-010, Brazil; Harris Birthright Research Center for Fetal Medicine, "'King's College Hospital and Department of Fetal Medicine, University College, London, United Kingdom.
Ricardo BariniDepartment of Obstetrics and Gynecology, Campinas University (UNICAMP), Campinas, SP, 13.083-887, Brazil.
Joanne Kwak-KimReproductive Medicine and Immunology, Obstetrics and Gynecology, Clinical Sciences Department, Chicago Medical School, Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, 60061, USA.
Universidade de Fortaleza · BRRosalind Franklin University of Medicine and Science · USUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal da Bahia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) pandemic has spread rapidly across the world. The vast majority of patients with COVID-19 manifest mild to moderate symptoms but may progress to severe cases or even mortalities. Young adults of reproductive age are the most affected population by SARS-CoV-2 infection. However, there is no consensus yet if pregnancy contributes to the severity of COVID-19. Initial studies of pregnant women have found that COVID-19 significantly increases the risk of preterm birth, intrauterine growth restriction, and low birth weight, which have been associated with non-communicable diseases in offspring. Besides, maternal viral infections with or without vertical transmission have been allied with neurological and behavioral disorders of the offspring. In this review, obstetrical outcomes of women with COVID-19 and possible risks for their offspring are discussed by reviewing maternal immune responses to COVID-19 based on the current evidence. Structural and systemic follow-up of offspring who are exposed to SARS-CoV-2 in-utero is suggested.

Indexed as

Child of Impaired ParentsCOVID-19FemaleFetal Growth RetardationHumansImmunity, Maternally-AcquiredInfectious Disease Transmission, VerticalMaternal ExposurePregnancyPregnancy Complications, InfectiousPregnancy OutcomePremature BirthProblem BehaviorRiskSARS-CoV-2Behavioral disordersCOVID-19Obstetrical outcomesOffspringSARS-CoV-2

Identifiers

PMID33249335
PMCPMC7676367
OpenAlexW3104859830

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.