ArticleBMJ open diabetes research & care2020
Long-term variability of glycemic markers and risk of all-cause mortality in type 2 diabetes: the Look AHEAD study.
Article in BMJ open diabetes research & care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- High-intensity interval training and continuous glucose monitoring-derived glycemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- HbA1c variability and risk of incident heart failure: A systematic review and meta-analysis.Biomolecules & biomedicine · 2025Pooled it
- Pooled it
- Glycemic variability of glycated hemoglobin in patients with type 2 diabetes mellitus and the risk of cardiovascular diseases: a latest systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Higher glucose fluctuation is associated with a higher risk of cardiovascular disease: Insights from pooled results among patients with diabetes.Journal of diabetes · 2023Pooled it
- Impact of COVID-19 Lockdown on the Metabolic Control Parameters in Patients with Diabetes Mellitus: A Systematic Review and Meta-Analysis.Diabetes & metabolism journal · 2022Pooled it
- Factors Associated With Predialysis Plasma Glucose Variability in Patients With Diabetes on Hemodialysis.International journal of endocrinology · 2026Article
- The Association Between Glycemic Variability and Mortality in Critically Ill Patients: A Multicenter Prospective Observational Study.Journal of clinical medicine · 2024Article
- Glycemic Variability As a Prognostic Factor for Mortality in Patients With Critical Illness: A Systematic Review and Meta-Analysis.Critical care explorations · 2024Review
- Individualized Glycemic Control in Type 2 Diabetic Patients in Iran: A Multi-Center Data Analysis.Iranian journal of medical sciences · 2023Article
- Oscillating Glucose Induces the Increase in Inflammatory Stress through Ninjurin-1 Up-Regulation and Stimulation of Transport Proteins in Human Endothelial Cells.Biomolecules · 2023Article
- Long-term glycemic variability predicts compromised development of heart failure with improved ejection fraction: a cohort study.Frontiers in endocrinology · 2023Article
- Day-to-day fasting plasma glucose variability on the short-term prognosis of ST-segment elevation myocardial infarction: A retrospective cohort study.Clinical cardiology · 2022Article
- HbA1c variability predicts cardiovascular complications in type 2 diabetes regardless of being at glycemic target.Cardiovascular diabetology · 2022Article
- The Association Between Mean Glycated Haemoglobin or Glycaemic Variability and the Development of Retinopathy in People with Diabetes: A Retrospective Observational Cohort Study.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021Article
- Glucose Variability: How Does It Work?International journal of molecular sciences · 2021Review
- Impact of type 2 diabetes and microvascular complications on mortality and cardiovascular outcomes in a multiethnic Asian population.BMJ open diabetes research & care · 2021Article
- Glycemic variability and cardiovascular disease in patients with type 2 diabetes.BMJ open diabetes research & care · 2021 · on this mapReview
- Effect of Hydroxychloroquine on Glycemic Variability in Type 2 Diabetes Patients Uncontrolled on Glimepiride and Metformin Therapy.Indian journal of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
introductionGlycemic variability may predict poor outcomes in type 2 diabetes. We evaluated the associations of long-term variability in glycosylated hemoglobin (HbA RESEARCH DESIGN AND
methodsWe conducted a secondary, prospective cohort analysis of the Look AHEAD (Action for Health in Diabetes) data, including 3560 participants who attended four visits (baseline, 12 months, 24 months, and 36 months) at the outset. Variability of HbA
resultsOver a median follow-up of 6.8 years, there were 164 deaths from any cause, 33 CVD-related deaths, 91 HF events, and 340 participants experienced the CVD composite. Adjusted HRs comparing the highest to lowest quartile of SD of HbA
conclusionsA greater variability in HbA
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.