Trial reportCurrent biology : CB2021
Prolonged, Controlled Daytime versus Delayed Eating Impacts Weight and Metabolism.
Erratum issuedOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph
Trial report in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 56 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 3 pooled it
5.4field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Circadian alignment of food intake and glycaemic control by time-restricted eating: A systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2024Pooled it
- Pooled it
- Pooled it
- Effects of later dinner timing on subsequent metabolic function and nocturnal sleep in healthy young women.Journal of physiological anthropology · 2026Trial
- Association between dim light melatonin onset predicted from gene expression profiles with sleep time and chronotype preference: A pilot study.Chronobiology international · 2025Trial
- Objective and subjective appetite measures: high versus low eating frequency in a randomized crossover clinical trial.Obesity (Silver Spring, Md.) · 2025Trial
- Design and Implementation of a Time-Restricted Eating Intervention in a Randomized, Controlled Eating Study.Nutrients · 2023Trial
- Impact of early time-restricted eating on diet quality, meal frequency, appetite, and eating behaviors: A randomized trial.Obesity (Silver Spring, Md.) · 2023Trial
- Delaying mealtimes reduces fat oxidation: A randomized, crossover, controlled feeding study.Obesity (Silver Spring, Md.) · 2022Trial
- Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity.Cell metabolism · 2022Trial
- Adherence to Diet and Meal Timing in a Randomized Controlled Feeding Study of Time-Restricted Feeding.Nutrients · 2022Trial
- Early time-restricted eating compared with daily caloric restriction: A randomized trial in adults with obesity.Obesity (Silver Spring, Md.) · 2022Trial
- An Earlier First Meal Timing Associates with Weight Loss Effectiveness in A 12-Week Weight Loss Support Program.Nutrients · 2022Trial
- Association between circadian rest-activity rhythm and meal timing: NHANES 2013-2014.Sleep health · 2026Article
- Understanding Postpartum Mothers' Perspectives of Chrononutrition Approaches: A Qualitative Study.Journal of the Academy of Nutrition and Dietetics · 2026Article
- A data-driven trajectory analysis reveals associations between temporal patterns of within-day energy intake and mortality risk in U.S. adults: NHANES 2005-2018.European journal of nutrition · 2026Article
- Article
- Translational applications of circadian research: connecting chronobiology to medicine.Npj biological timing and sleep · 2026Review
- Chrononutrition and cardiometabolic health: circadian timing as a dimension of precision nutrition.Frontiers in nutrition · 2026Review
- Effects of timing and eating duration of time restricted eating on metabolic outcomes: systematic review and network meta-analysis.BMJ medicine · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 4 institutions in 1 country.
Kelly C AllisonCenter for Weight and Eating Disorders, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: kca@pennmedicine.upenn.edu.
Christina M HopkinsCenter for Weight and Eating Disorders, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Madelyn RuggieriCenter for Weight and Eating Disorders, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Andrea M SpaethDepartment of Kinesiology and Health, Rutgers University, New Brunswick, NJ 08901, USA.
Rexford S AhimaDivision of Endocrinology, Diabetes and Metabolism, Johns Hopkins University, Baltimore, MD 21287, USA.
Zhe ZhangDepartment of Biomedical Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Deanne M TaylorDepartment of Biomedical Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Namni GoelDivision of Sleep and Chronobiology, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA; Biological Rhythms Research Laboratory, Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA.
University of Pennsylvania · USChildren's Hospital of Philadelphia · USJohns Hopkins University · USRutgers, The State University of New Jersey · US
Funding
Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0MVIRAL VECTOR COREP30DK019525 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI JOSHUA D RABINOWITZ · 1986 to 2026
$48.3MInstitutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9MResearch BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3MImpact of Daytime vs. Delayed Eating Schedule on Weight and Metabolic Markers Among Obese Persons: An Examination of Circadian MechanismsR01DK117488 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI ALLISON, KELLY C, GOEL, NAMNI · 2017 to 2021
$3.8MRandomized study of daytime vs. delayed eating: Effect on weight and metabolismR21DK100787 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI ALLISON, KELLY C · 2014 to 2015
$440kNCATS NIH HHS UL1 TR000003NCATS NIH HHS UL1 TR001873NIDDK NIH HHS P30 DK019525NIDDK NIH HHS P30 DK072488NIDDK NIH HHS R01 DK117488NIDDK NIH HHS R21 DK100787
Abstract
A delayed eating schedule is associated with increased risk of obesity and metabolic dysfunction in humans.
Indexed as
EatingAdultCircadian RhythmCross-Over StudiesEnergy MetabolismFemaleGlucoseHumansInsulinInsulin ResistanceMaleObesityYoung AdultGlucoseInsulincircadian rhythmsmetabolismnighttime eatingtimed eatingtime restricted feedingweight
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.