Evidence map›Paper›PMID 33264354›Full record

ArticlePloS one2020

Associations between preconception macronutrient intake and birth weight across strata of maternal BMI.

Nastaran Salavati, Marian K Bakker, Fraser Lewis, Petra C Vinke, Farya Mubarik, JanJaap H M Erwich, Eline M van der Beek

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Environmental Exposures around Conception: Developmental Pathways Leading to Lifetime Disease Risk.International journal of environmental research and public health · 2021
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nastaran SalavatiDepartment of Obstetrics and Gynecology, University Medical Centre of Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-6244-4841
Marian K BakkerDepartment of Obstetrics and Gynecology, University Medical Centre of Groningen, University of Groningen, Groningen, The Netherlands.
Fraser LewisDanone Nutricia Research, Utrecht, The Netherlands.
Petra C VinkeDepartment of Epidemiology, University Medical Centre of Groningen, University of Groningen, Groningen, The Netherlands.
Farya MubarikDepartment of Obstetrics and Gynecology, University Medical Centre of Groningen, University of Groningen, Groningen, The Netherlands.
JanJaap H M ErwichDepartment of Obstetrics and Gynecology, University Medical Centre of Groningen, University of Groningen, Groningen, The Netherlands.
Eline M van der BeekDanone Nutricia Research, Utrecht, The Netherlands.
University Medical Center Groningen · NLDanone (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMaternal nutrition during pregnancy is linked with birth outcomes including fetal growth, birth weight, congenital anomalies and long-term health through intra-uterine programming. However, a woman's nutritional status before pregnancy is a strong determinant in early embryo-placental development, and subsequently outcomes for both mother and child. Therefore, the aim of this study was to investigate the association between dietary macronutrient intake in the preconception period with birth weight.

methodsWe studied a group of 1698 women from the Dutch Perined-Lifelines linked birth cohort with reliable detailed information on preconception dietary macronutrient intake (using a semi quantitative food frequency questionnaire) and data available on birth weight of the offspring. Birth weight was converted into gestational age adjusted z-scores, and macronutrient intake was adjusted for total energy intake using the nutrient residual method. Preconception BMI was converted into cohort-based quintiles. Multivariable linear regression was performed, adjusted for other macronutrients and covariates.

resultsMean maternal age was 29.5 years (SD 3.9), preconception BMI: 24.7 kg/m2 (SD 4.2) and median daily energy intake was 1812 kcal (IQR 1544-2140). Mean birth weight was 3578 grams (SD 472). When adjusted for covariates, a significant association (adjusted z score [95% CI], P) between polysaccharides and birth weight was shown (0.08 [0.01-0.15], 0.03). When linear regression analyses were performed within cohort-based quintiles of maternal BMI, positive significant associations between total protein, animal protein, fat, total carbohydrates, mono-disaccharides and polysaccharides with birth weight were shown in the lowest quintile of BMI independent of energy intake, intake of other macronutrients and covariates.

conclusionOut of all macronutrients studied, polysaccharides showed the strongest association with birth weight, independent of energy intake and other covariates. Our study might suggest that specifically in women with low preconception BMI a larger amount of macronutrient intake was associated with increased birth weight. We recommend that any dietary assessment and advise during preconception should be customized to preconception weight status of the women.

Indexed as

Birth WeightNutritional StatusAdultBody Mass IndexCohort StudiesFemaleHumansLinear ModelsMaternal AgeMaternal Nutritional Physiological PhenomenaNutrientsPregnancyNutrients

Identifiers

PMID33264354
PMCPMC7710031
OpenAlexW3110144239

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.