Evidence map›Paper›PMID 33266487›Full record

ArticleNutrients2020

Dietary Acrylamide Intake and the Risk of Pancreatic Cancer: The Japan Public Health Center-Based Prospective Study.

Kumiko Kito, Junko Ishihara, Ayaka Kotemori, Ling Zha, Rong Liu, Norie Sawada, Motoki Iwasaki, Tomotaka Sobue, Shoichiro Tsugane

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Understanding exposomes and its relation with cancer risk in Malaysia based on epidemiological evidence: a narrative review.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2024
    Review
  6. Article
  7. Exposure to environmental chemicals and cancer risk: epidemiological evidence from Japanese studies.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2023
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kumiko KitoGraduate School of Environmental Health, Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan.
Junko IshiharaDepartment of Food and Life Science, Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan.ORCID 0000-0002-9516-5646
Ayaka KotemoriDepartment of Food and Life Science, Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan.ORCID 0000-0003-3954-8615
Ling ZhaDepartment of Environmental Medicine and Population Sciences, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.ORCID 0000-0003-4668-4199
Rong LiuDepartment of Environmental Medicine and Population Sciences, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.ORCID 0000-0003-2688-4943
Norie SawadaEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Motoki IwasakiEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Tomotaka SobueDepartment of Environmental Medicine and Population Sciences, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.ORCID 0000-0003-2817-3483
Shoichiro TsuganeEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.ORCID 0000-0003-4105-2774
Azabu University · JPThe University of Osaka · JP

Funding

a Grant-in-Aid for Cancer Research from the Ministry of Health, Labour and Welfare of Japan 1989-2010; the principal investigator from 1997 to 2010 was S. Tsuganethe Food Safety Commission, Cabinet Office, Government of Japan Research Program for Risk Assessment Study on Food Safety, no. 1503; the principal investigator was T. Sobue and no. 1904; principal investigator was J. Ishiharathe National Cancer Center Research and Development Fund since 2011; the principal investigator was S. Tsugane
6 · The paper itself

Abstract

Acrylamide is a probable carcinogen in humans. Few studies have assessed dietary acrylamide intake and the risk of pancreatic cancer; however, these studies are based on Western populations. Our purpose was to investigate the association of dietary acrylamide intake with the risk of pancreatic cancer utilizing data from the Japan Public Health Center-based Prospective Study. We evaluated the data of 89,729 participants aged 45-74 years, who replied to a questionnaire on past medical history and lifestyle habits from 1995-1998. Dietary acrylamide intake was estimated utilizing a validated food frequency questionnaire. We calculated the hazard ratios and 95% confidence intervals by using Cox proportional-hazards regression models. The average follow-up was 15.2 years, and 576 cases of pancreatic cancer were diagnosed. In the multivariate-adjusted model, an association between dietary acrylamide intake and pancreatic cancer risk was not demonstrated (hazard ratio for the highest vs. lowest quartile = 0.83, 95% confidence interval: 0.65-1.05,

Indexed as

DietAcrylamideAgedCandyCoffeeEnergy IntakeFemaleHumansJapanMaleMiddle AgedPancreatic NeoplasmsProportional Hazards ModelsProspective StudiesRisk FactorsSurveys and QuestionnairesAcrylamideCoffeeTeaacrylamideAsiadietepidemiologic studypancreatic cancer

Identifiers

PMID33266487
PMCPMC7700165
OpenAlexW3107262585

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.