Evidence map›Paper›PMID 33283595›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2021

Safety and efficacy of symptomatic carotid artery stenting performed in an emergency setting.

Darko Quispe-Orozco, Kaustubh Limaye, Cynthia B Zevallos, Mudassir Farooqui, Alan Mendez-Ruiz, Sameer Ansari, Andres Dajles, Edgar A Samaniego, Colin Derdeyn, Santiago Ortega-Gutierrez

Abstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Darko Quispe-OrozcoDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.ORCID https://orcid.org/0000-0003-3627-5439
Kaustubh LimayeDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Cynthia B ZevallosDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.ORCID https://orcid.org/0000-0001-8715-240X
Mudassir FarooquiDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Alan Mendez-RuizDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Sameer AnsariDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Andres DajlesDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Edgar A SamaniegoDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Colin DerdeynDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Santiago Ortega-GutierrezDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007337 · NIGMS · UNIVERSITY OF IOWA · PI GEYER, PAMELA K., LENTZ, STEVEN R · 1985 to 2020
$15.9M
NIGMS NIH HHS T32 GM007337
6 · The paper itself

Abstract

introductionCarotid artery stenting (CAS) has increasingly emerged as an alternative strategy to carotid endarterectomy in the treatment of patients with symptomatic carotid stenosis. Optimal timing for CAS after symptoms onset remains unclear. We aimed to evaluate the safety and efficacy of CAS when performed in an emergency setting. PATIENTS AND

methodsWe performed a retrospective analysis of CAS patients admitted to our CSC with symptomatic extracranial carotid occlusion or significant stenosis from January 2014-September 2019. Emergency CAS was defined as CAS performed during the same hospitalization from TIA/stroke onset, whereas elective CAS as CAS performed on a subsequent admission. The primary outcome was defined as the occurrence of any stroke, myocardial infarction, or death related to the procedure at 3 months of follow-up. Secondary outcomes included periprocedural complications and the rate of restenosis/occlusion at follow-up. Logistic regression and survival analyses were used to compare outcomes and restenosis at follow-up.

resultsWe identified 75 emergency and 104 elective CAS patients. Emergency CAS patients had significantly higher rates of ipsilateral carotid occlusion (17% vs. 2%, p < 0.001) and use of general anesthesia (19% vs. 4%, p = 0.001) than elective CAS. There were no significant differences between emergency and elective CAS in the primary (5.7% vs. 1%, p = 0.161) and secondary (9% vs. 4.8%, p = 0.232) outcomes. We did not find differences in the rate of restenosis/occlusion (7% vs. 11.6%; log-rank test p = 0.3) at a median of 13 months follow-up.

conclusionIn our study, emergency CAS in symptomatic patients might have a similar safety and efficacy profile to elective CAS at 3 months and long-term follow-up.

Indexed as

Carotid StenosisEndarterectomy, CarotidStrokeCarotid ArteriesHumansRetrospective StudiesRisk FactorsStentsTreatment Outcomecarotid artery stenting.mechanical thrombectomySymptomatic carotid artery stenosis

Identifiers

PMID33283595
PMCPMC8190945

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.