Evidence map›Paper›PMID 33288541›Full record

ReviewCold Spring Harbor perspectives in biology2021

Emerging Properties and Functions of Actin and Actin Filaments Inside the Nucleus.

Svenja Ulferts, Bina Prajapati, Robert Grosse, Maria K Vartiainen

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. pH-regulated nuclear F-actin assembly during ferroptosis.Frontiers in cell and developmental biology · 2025
    Article
  10. Article
  11. Article
  12. Nuclear actin is a critical regulator ofbioRxiv : the preprint server for biology · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. The multiple links between actin and mitochondria.Nature reviews. Molecular cell biology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Svenja UlfertsInstitute for Clinical and Experimental Pharmacology and Toxicology I, University of Freiburg, 79104 Freiburg, Germany.
Bina PrajapatiInstitute of Biotechnology, Helsinki Institute for Life Science, University of Helsinki, 00014 Helsinki, Finland.
Robert GrosseInstitute for Clinical and Experimental Pharmacology and Toxicology I, University of Freiburg, 79104 Freiburg, Germany.
Maria K VartiainenInstitute of Biotechnology, Helsinki Institute for Life Science, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0002-2017-0475

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent years have provided considerable insights into the dynamic nature of the cell nucleus, which is constantly reorganizing its genome, controlling its size and shape, as well as spatiotemporally orchestrating chromatin remodeling and transcription. Remarkably, it has become clear that the ancient and highly conserved cytoskeletal protein actin plays a crucial part in these processes. However, the underlying mechanisms, regulations, and properties of actin functions inside the nucleus are still not well understood. Here we summarize the diverse and distinct roles of monomeric and filamentous actin as well as the emerging roles for actin dynamics inside the nuclear compartment for genome organization and nuclear architecture.

Indexed as

Actin CytoskeletonActinsAllosteric RegulationCell NucleusChromatin Assembly and DisassemblyDNA-Directed RNA PolymerasesTranscription, GeneticActinsDNA-Directed RNA Polymerases

Identifiers

PMID33288541
PMCPMC7919393

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.