ArticleAging2020
Development and validation of prognostic nomograms for early-onset locally advanced colon cancer.
Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Surgical treatment of locally advanced right colon cancer invading neighboring organs.Frontiers in medicine · 2022Pooled it
- Establishment and validation of a prognostic nomogram for patients with early-onset stage I-II colon cancer.World journal of surgical oncology · 2023Trial
- Characteristics of Prognostic Programmed Cell Death-Related Long Noncoding RNAs Associated With Immune Infiltration and Therapeutic Responses to Colon Cancer.Frontiers in immunology · 2022Trial
- Prognostic nomogram to predict the overall survival of patients with early-onset colorectal cancer: a population-based analysis.International journal of colorectal disease · 2021Trial
- A predictive nomogram for predicting liver metastasis in early-onset colon cancer: a population-based study.Translational cancer research · 2025Article
- Development and validation of a risk predictive nomogram for colon cancer-specific mortality: a competing risk model based on the SEER database.Discover oncology · 2024Article
- The Use of Artificial Intelligence in Predicting Chemotherapy-Induced Toxicities in Metastatic Colorectal Cancer: A Data-Driven Approach for Personalized Oncology.Diagnostics (Basel, Switzerland) · 2024Article
- The advanced lung cancer inflammation index (ALI) predicted the postoperative survival rate of patients with non-small cell lung cancer and the construction of a nomogram model.World journal of surgical oncology · 2024Article
- Construction and validation of a nomogram for predicting overall survival of patients with stage III/IV early-onset colorectal cancer.Frontiers in oncology · 2024Article
- Establishment and validation of nomogram models for overall survival and cancer-specific survival in spindle cell sarcoma patients.Scientific reports · 2023Article
- Advantage of log odds of positive lymph nodes in prognostic evaluation of patients with early-onset colon cancer.World journal of gastrointestinal surgery · 2023Article
- Development and validation of prognostic nomograms for early-onset colon cancer in different tumor locations: a population-based study.BMC gastroenterology · 2023Article
- Predicting survival and prognosis in early-onset locally advanced colon cancer: a retrospective observational study.International journal of colorectal disease · 2023Observational
- A narrative review of prognostic indices in the evaluation of gastrointestinal cancers.Journal of gastrointestinal oncology · 2023Review
- Correlation between overall survival and quality of life in colon cancer patients with chemotherapy.BMC cancer · 2023Article
- Causes of death among early-onset colorectal cancer population in the United States: a large population-based study.Frontiers in oncology · 2023Article
- A novel prognostic model for patients with colon adenocarcinoma.Frontiers in endocrinology · 2023Article
- Establishment and validation of a postoperative predictive model for patients with colorectal mucinous adenocarcinoma.World journal of surgical oncology · 2022Article
- Nomogram predicting the cancer-specific survival of early-onset colorectal cancer patients with synchronous liver metastasis: a population-based study.International journal of colorectal disease · 2022Article
- Construction of Novel Prognostic Nomogram for Mucinous and Signet Ring Cell Colorectal Cancer Patients with a Survival Longer Than 5 Years.International journal of general medicine · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of colorectal cancer in patients younger than 50 years has been increasing in recent years.
objectiveDevelop and validate prognostic nomograms predicting overall survival (OS) and cancer-specific survival (CSS) for early-onset locally advanced colon cancer (EOLACC) based on the Surveillance, Epidemiology, and End Results (SEER) database.
resultsThe entire cohort comprised 13,755 patients with EOLACC. The nomogram predicting OS for EOLACC displayed that T stage contributed the most to prognosis, followed by N stage, regional nodes examined (RNE) and surgery. The nomogram predicting CSS for EOLACC demonstrated similar results. Various methods identified the discriminating superiority of the nomograms. X-tile software was used to classify patients into high-risk, medium-risk, and low-risk according to the risk score of the nomograms. The risk stratification effectively avoided the survival paradox.
conclusionsWe established and validated nomograms for predicting OS and CSS based on a national cohort of almost 13,000 EOLACC patients. The nomograms could effectively solve the issue of survival paradox of the AJCC staging system and be an excellent tool to integrate the clinical characteristics to guide the therapeutic choice for EOLACC patients.
methodsNomograms were constructed based on the SEER database and the Cox regression model.
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