Evidence map›Paper›PMID 33290767›Full record

ArticleInternational journal of biological macromolecules2021

Assessment of antiviral potencies of cannabinoids against SARS-CoV-2 using computational and in vitro approaches.

Vinit Raj, Jae Gyu Park, Kiu-Hyung Cho, Pilju Choi, Taejung Kim, Jungyeob Ham, Jintae Lee

Open access · greenAbstract read
In one paragraph

Article in International journal of biological macromolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Selected Cannabinoids, Cannabimimetic Agents andPharmaceuticals (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Anti-Infective Screening of Selected Nine Cannabinoids AgainstCurrent issues in molecular biology · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Current and Potential Use of Biologically Active Compounds Derived fromInternational journal of molecular sciences · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Vinit RajSchool of Chemical Engineering, Yeungnam University, Gyeongsan, Republic of Korea.
Jae Gyu ParkAdvanced Bio Convergence Center, Pohang Technopark Foundation, Pohang, Republic of Korea.
Kiu-Hyung ChoGyeongbuk Institute for Bio industry, Andong, Republic of Korea.
Pilju ChoiNatural Products Research Institute, Korea Institute of Science and Technology (KIST), Gangneung, Republic of Korea.
Taejung KimNatural Products Research Institute, Korea Institute of Science and Technology (KIST), Gangneung, Republic of Korea.
Jungyeob HamNatural Products Research Institute, Korea Institute of Science and Technology (KIST), Gangneung, Republic of Korea; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology (UST), Seoul, Republic of Korea. Electronic address: ham0606@kist.re.kr.
Jintae LeeSchool of Chemical Engineering, Yeungnam University, Gyeongsan, Republic of Korea. Electronic address: jtlee@ynu.ac.kr.
Korea Institute of Science and Technology · KRYeungnam University · KRGyeongbuk Marine Bio-Industry Research Institute · KRKorea University of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective treatment choices to the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are limited because of the absence of effective target-based therapeutics. The main object of the current research was to estimate the antiviral activity of cannabinoids (CBDs) against the human coronavirus SARS-CoV-2. In the presented research work, we performed in silico and in vitro experiments to aid the sighting of lead CBDs for treating the viral infections of SARS-CoV-2. Virtual screening was carried out for interactions between 32 CBDs and the SARS-CoV-2 M

Indexed as

COVID-19 Drug TreatmentAntiviral AgentsCannabidiolCannabinoidsComputer SimulationCoronavirus 3C ProteasesCOVID-19DronabinolDrug Evaluation, PreclinicalHumansIn Vitro TechniquesLigandsModels, BiologicalMolecular Docking SimulationMolecular Dynamics SimulationPandemics3C-like proteinase, SARS-CoV-2Antiviral AgentsCannabidiolCannabinoidsCoronavirus 3C ProteasesDronabinolLigandsProtease InhibitorsCannabinolsIn vitro antiviral assaySARS-CoV-2 and M(pro) enzyme

Identifiers

PMID33290767
PMCPMC7836687
OpenAlexW3112965324

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.