Evidence map›Paper›PMID 33305939›Full record

ArticleACS sensors2020

Systematic Comparison of Vesicular Targeting Signals Leads to the Development of Genetically Encoded Vesicular Fluorescent Zn

Evan P S Pratt, Kelsie J Anson, Justin K Tapper, David M Simpson, Amy E Palmer

Open access · greenAbstract read
In one paragraph

Article in ACS sensors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Redesign of Calmodulin for Genetically Encoded ZnChemical & biomedical imaging · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Evan P S PrattDepartment of Biochemistry and BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, UCB 596, Boulder, Colorado 80309-0401, United States.
Kelsie J AnsonDepartment of Biochemistry and BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, UCB 596, Boulder, Colorado 80309-0401, United States.ORCID 0000-0001-5941-0547
Justin K TapperDepartment of Biochemistry and BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, UCB 596, Boulder, Colorado 80309-0401, United States.
David M SimpsonDepartment of Biochemistry and BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, UCB 596, Boulder, Colorado 80309-0401, United States.
Amy E PalmerDepartment of Biochemistry and BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, UCB 596, Boulder, Colorado 80309-0401, United States.ORCID 0000-0002-5794-5983
University of Colorado Boulder · US

Funding

Predoctoral Training Molecular BiophysicsT32GM065103 · NIGMS · UNIVERSITY OF COLORADO AT BOULDER · PI FALKE, JOSEPH J · 2002 to 2021
$4.3M
Regulation of Cell Signaling by Transition Metal DynamicsDP1GM114863 · NIGMS · UNIVERSITY OF COLORADO · PI PALMER, AMY E · 2014 to 2018
$3.8M
ImageXpress Micro Cellular Imagining and Analysis SystemS10RR026680 · NCRR · UNIVERSITY OF COLORADO · PI LIU, XUEDONG · 2011 to 2011
$380k
NCRR NIH HHS S10 RR026680NIGMS NIH HHS DP1 GM114863NIGMS NIH HHS T32 GM065103
6 · The paper itself

Abstract

Genetically encoded fluorescent sensors have been widely used to illuminate secretory vesicle dynamics and the vesicular lumen, including Zn

Indexed as

Fluorescence Resonance Energy TransferZincCell LineHumansHydrogen-Ion ConcentrationSecretory VesiclesZincchromogranin Afluorescent sensorFRETgenetically encodedpHsecretory vesicletargeting signalzinc

Identifiers

PMID33305939
PMCPMC8444068
OpenAlexW3111177048

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.