Evidence map›Paper›PMID 33312536›Full record

ArticleFood science & nutrition2020

Novel high-docosahexaenoic-acid tuna oil supplementation modulates gut microbiota and alleviates obesity in high-fat diet mice.

Jing Zhang, Congmin Yi, Jiaojiao Han, Tinghong Ming, Jun Zhou, Chenyang Lu, Ye Li, Xiurong Su

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jing ZhangState Key Laboratory for Quality and Safety of Argo-products Ningbo University Ningbo China.
Congmin YiState Key Laboratory for Quality and Safety of Argo-products Ningbo University Ningbo China.
Jiaojiao HanState Key Laboratory for Quality and Safety of Argo-products Ningbo University Ningbo China.
Tinghong MingState Key Laboratory for Quality and Safety of Argo-products Ningbo University Ningbo China.
Jun ZhouState Key Laboratory for Quality and Safety of Argo-products Ningbo University Ningbo China.
Chenyang LuState Key Laboratory for Quality and Safety of Argo-products Ningbo University Ningbo China.
Ye LiState Key Laboratory for Quality and Safety of Argo-products Ningbo University Ningbo China.
Xiurong SuState Key Laboratory for Quality and Safety of Argo-products Ningbo University Ningbo China.ORCID https://orcid.org/0000-0003-2336-191X
Ningbo University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have documented the benefits of fish oil in different diseases because of its high n-3 polyunsaturated fatty acid content. However, these studies mostly used commercially available fish oil supplements with a ratio of 18/12 for eicosapentaenoic acid and docosahexaenoic acid (DHA). However, increasing DHA content for this commonly used ratio might bring out a varied metabolic effect, which have remained unclear. Thus, in this study, a novel tuna oil (TO) was applied to investigate the effect of high-DHA content on the alteration of the gut microbiota and obesity in high-fat diet mice. The results suggest that high-DHA TO (HDTO) supplementation notably ameliorates obesity and related lipid parameters and restores the expression of lipid metabolism-related genes. The benefits of TOs were derived from their modification of the gut microbiota composition and structure in mice. A high-fat diet triggered an increased

Indexed as

dietary obesitygut microbiotanovel high‐DHA tuna oil

Identifiers

PMID33312536
PMCPMC7723182
OpenAlexW3105367805

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.