Evidence map›Paper›PMID 33312700›Full record

ArticleFuture science OA2020

The value of anti-epileptic therapy as a prophylactic factor for seizures in the management of moderate traumatic brain injury.

Konstantinos Faropoulos, Demosthenes Makris, George Fotakopoulos

Open access · goldAbstract read
In one paragraph

Article in Future science OA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Konstantinos FaropoulosDepartment of Neurosurgery, Nicosia General Hospital, Nicosia, Cyprus.
Demosthenes MakrisDepartment of Head of Critical Care, University Hospital of Larissa, Larissa, Greece.
George FotakopoulosDepartment of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Larissa, Greece.ORCID https://orcid.org/0000-0002-2491-2886
University Hospital of Larissa · GRNicosia General Hospital · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe value of anti-epileptic therapy in the prophylaxis of post-traumatic seizures. PATIENTS &

methodsAll patients received a standard anti-epileptic drug (AED) and were divided into two groups: Group A -with early AED and Group B -with late AED.

resultsPatients (871/1062) met the inclusion criteria. Multivariate analysis demonstrated that computer tomography findings, headache and prior history of brain head injury were independent risk factors of seizures. Only late post-traumatic seizures (LPTS) was significantly associated with AED (p < 0.05).

conclusionEarly treatment with AED seems to not affect the incidence of lPTS. In addition, an AED with a mean time of initiation of 7.5 days from the moderate traumatic brain injury occurrence could reduce the lPTS incidence.

Indexed as

anti-epileptic drugsbrain traumaearly seizureselectroencephalogramlate seizureslevetiracetammoderate traumatic brain injurypost-traumatic seizuresprophylactic anti-epileptic therapysingle post-traumatic seizures

Identifiers

PMID33312700
PMCPMC7720367
OpenAlexW3082227159

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.