Evidence map›Paper›PMID 33313952›Full record

ArticleMolecular medicine reports2021

Inhibition of SNCG suppresses the proliferation of lung cancer cells induced by high glucose.

Jing Fei, Chi Xiao, Meiying Yang, Xue Zhou, Ping Gong

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Cancer in pathologically confirmed multiple system atrophy.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jing FeiDepartment of Oncology, The First Affiliated Hospital, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, P.R. China.
Chi XiaoDepartment of Clinical Medicine, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, P.R. China.
Meiying YangDepartment of Clinical Medicine, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, P.R. China.
Xue ZhouDepartment of Clinical Medicine, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, P.R. China.
Ping GongDepartment of Oncology, The First Affiliated Hospital, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, P.R. China.
Shihezi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the most common cancer type worldwide and the leading cause of cancer-related mortality. Diabetes is closely associated with the occurrence, development and prognosis of lung cancer. Therefore, the present study aimed to investigate whether SNCG could affect the proliferation of lung cancer cells induced by high glucose. Lung cancer cells induced by high glucose simulated the pathologies of patients with lung cancer with diabetes

Indexed as

Cell Line, TumorCell MovementCell Proliferationgamma-SynucleinGene Knockdown TechniquesGlucoseHumansInflammationInsulin-Like Growth Factor IInterleukin-6JNK Mitogen-Activated Protein KinasesLung NeoplasmsMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Neoplasm ProteinsPodophyllotoxingamma-SynucleinGlucoseIGF1 protein, humanIGF1R protein, humanIL6 protein, humanInsulin-Like Growth Factor IInterleukin-6JNK Mitogen-Activated Protein KinasesMAPK1 protein, humanMAPK3 protein, humanMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Neoplasm ProteinspicropodophyllinPodophyllotoxinReceptor, IGF Type 1SNCG protein, humanTNF protein, humanTumor Necrosis Factor-alphahigh glucoselung cancer cellsproliferationsynuclein γ

Identifiers

PMID33313952
PMCPMC7751455
OpenAlexW3112434924

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.