Evidence map›Paper›PMID 33318018›Full record

ArticleAntimicrobial agents and chemotherapy2021

Efficacy of Rezafungin in Prophylactic Mouse Models of Invasive Candidiasis, Aspergillosis, and

Lynn Miesel, Melanie T Cushion, Alan Ashbaugh, Santiago R Lopez, Voon Ong

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Rezafungin as Primary Prophylaxis ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Review
  6. Fungal biofilms in human health and disease.Nature reviews. Microbiology · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. Incidence ofJournal of fungi (Basel, Switzerland) · 2023
    Review
  11. New Approaches to Manage Infections in Transplant Recipients: Report From the 2023 GTI (Infection and Transplantation Group) Annual Meeting.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  12. Echinocandins - structure, mechanism of action and use in antifungal therapy.Journal of enzyme inhibition and medicinal chemistry · 2022
    Review
  13. The Pathogenesis and Diagnosis ofJournal of fungi (Basel, Switzerland) · 2022
    Review
  14. Review
  15. Biocontrol ofAntibiotics (Basel, Switzerland) · 2022
    Review
  16. Article
  17. Diagnosis and Treatment of Invasive Candidiasis.Antibiotics (Basel, Switzerland) · 2022
    Review
  18. Metabolism, Excretion, and Mass Balance of [Antimicrobial agents and chemotherapy · 2022
    Article
  19. On the Treatment ofOpen forum infectious diseases · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lynn MieselPharmacology Discovery Services, Taipei, Taiwan.
Melanie T CushionUniversity of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Alan AshbaughUniversity of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Santiago R LopezTransPharm Preclinical Solutions, Inc., Jackson, Michigan, USA.
Voon OngCidara Therapeutics, Inc., San Diego, California, USA vong@cidara.com.ORCID 0000-0001-8676-6717
Cincinnati VA Medical Center · USCidara Therapeutics (United States) · USClinical Solutions · US

Funding

The role of sex in the life cycle and transmission of PneumocystisR01HL146266 · NHLBI · UNIVERSITY OF CINCINNATI · PI CUSHION, MELANIE T · 2019 to 2022
$1.9M
The role of sex in the life cycle of PneumocystisI01BX004441 · VA · CINCINNATI VA MEDICAL CENTER RESEARCH · PI ALAN George Smulian · 2019 to 2026
–
BLR&D Research Career Scientist Award ApplicationIK6BX005232 · VA · CINCINNATI VA MEDICAL CENTER RESEARCH · PI Melanie T Cushion · 2020 to 2026
–
BLRD VA I01 BX004441BLRD VA IK6 BX005232NHLBI NIH HHS R01 HL146266
6 · The paper itself

Abstract

Antifungal prophylaxis is recommended to prevent invasive fungal disease caused by

Indexed as

AspergillosisCandidiasis, InvasivePneumonia, PneumocystisAnimalsAntifungal AgentsEchinocandinsHumansMiceMicrobial Sensitivity TestsAntifungal AgentsEchinocandinsRezafunginantifungal agentsantifungal therapyAspergillusCandidaechinocandinPneumocystisprophylaxis

Identifiers

PMID33318018
PMCPMC8092522
OpenAlexW3111683278

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.