Evidence map›Paper›PMID 33327816›Full record

ArticleThe Journal of international medical research2020

Using intestinal flora to distinguish non-alcoholic steatohepatitis from non-alcoholic fatty liver.

Chao Li, Lihong Cui, Xiaohui Wang, Zhihui Yan, Shaoxin Wang, Yan Zheng

Abstract read
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Alteration of small intestinal microbiota in diet-induced steatohepatitis mice.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Microbiota-derived HNature communications · 2025
    Article
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  11. Article
  12. Article
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  14. Frontiers in cellular and infection microbiology · 2023
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chao LiMedical School of Chinese PLA, Beijing, China.
Lihong CuiMedical School of Chinese PLA, Beijing, China.ORCID https://orcid.org/0000-0003-3007-728X
Xiaohui WangDepartment of Gastroenterology, the Sixth Medical Center, Chinese PLA General Hospital, Beijing, China.
Zhihui YanDepartment of Gastroenterology, the Sixth Medical Center, Chinese PLA General Hospital, Beijing, China.
Shaoxin WangDepartment of Gastroenterology, the Sixth Medical Center, Chinese PLA General Hospital, Beijing, China.
Yan ZhengDepartment of Gastroenterology, the Sixth Medical Center, Chinese PLA General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore specific flora in mouse models of non-alcoholic steatohepatitis (NASH) to improve NASH diagnostic protocols.

methodsSixty mice were divided into normal diet (ND, 20 mice) and high-fat/high-sugar diet (HFSD) groups (40 mice). After 8 weeks of feeding, 10 mice in the ND group and 20 mice in the HFSD group were sacrificed to create the short-term ND and non-alcoholic fatty liver (NAFL) groups, respectively. After 16 weeks of feeding, the remaining mice were sacrificed to create the long-term ND and NASH groups, respectively. We then examined fecal flora, serum biochemical indices, and lipopolysaccharide and tumor necrosis factor-α levels and analyzed liver tissue.

resultsThe relative abundance of

conclusionsThe relative abundance of

Indexed as

Gastrointestinal MicrobiomeNon-alcoholic Fatty Liver DiseaseAnimalsDiet, High-FatDisease Models, AnimalLiverMiceDesulfovibrioendotoxinhigh fat/high sugar dietintestinal floraLactobacillusNon-alcoholic fatty liver diseasenon-alcoholic steatohepatitisRuminiclostridiumTuricibacter

Identifiers

PMID33327816
PMCPMC7747123

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.