Evidence map›Paper›PMID 33329150›Full record

ArticleFrontiers in psychiatry2020

Does Chronic Cannabis Use Impact Risky Decision-Making: An Examination of fMRI Activation and Effective Connectivity?

David R Raymond, Adrian Paneto, Karmen K Yoder, Brian F O'Donnell, Joshua W Brown, William P Hetrick, Sharlene D Newman

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

David R RaymondDepartment of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, IN, United States.
Adrian PanetoDepartment of Counseling Psychology, Indiana University Bloomington, Bloomington, IN, United States.
Karmen K YoderDepartment of Radiology, Indiana University Medical School, Indianapolis, IN, United States.
Brian F O'DonnellDepartment of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, IN, United States.
Joshua W BrownDepartment of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, IN, United States.
William P HetrickDepartment of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, IN, United States.
Sharlene D NewmanDepartment of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, IN, United States.
Indiana University Bloomington · USIndiana University – Purdue University Indianapolis · US

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Graph Theoretic Analysis of Brain Networks in Cannabis UsersR21DA035493 · NIDA · TRUSTEES OF INDIANA UNIVERSITY · PI O'DONNELL, BRIAN FRANCIS · 2014 to 2015
$426k
NCATS NIH HHS UL1 TR002529NIDA NIH HHS R21 DA035493
6 · The paper itself

Abstract

With the increase in use of cannabis and its shifting legal status in the United States, cannabis use has become an important research focus. While studies of other drug populations have shown marked increases in risky decision-making, the literature on cannabis users is not as clear. The current study examined the performance of 17 cannabis users and 14 non-users on the Balloon Analog Risk Task (BART) using behavioral, fMRI and effective connectivity methods. Significant attenuation was found in a functional pathway projecting from the dorsal anterior cingulate cortex (dACC) to the nucleus accumbens (NAc) in cannabis users compared to non-using controls as well as decreases in risk-taking behaviors. These findings suggest that cannabis users may process and evaluate risks and rewards differently than non-users.

Indexed as

cannabisdecision-makingeffective connectivityfMRIrewardrisk

Identifiers

PMID33329150
PMCPMC7728610
OpenAlexW3107455068

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.