Evidence map›Paper›PMID 33330588›Full record

ReviewFrontiers in nutrition2020

Bioactive Compounds for the Management of Hypertriglyceridemia: Evidence From Clinical Trials and Putative Action Targets.

Elisabetta Schiano, Giuseppe Annunziata, Roberto Ciampaglia, Fortuna Iannuzzo, Maria Maisto, Gian Carlo Tenore, Ettore Novellino

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Elisabetta SchianoDepartment of Pharmacy, University of Naples Federico II, Naples, Italy.
Giuseppe AnnunziataDepartment of Pharmacy, University of Naples Federico II, Naples, Italy.
Roberto CiampagliaDepartment of Pharmacy, University of Naples Federico II, Naples, Italy.
Fortuna IannuzzoDepartment of Pharmacy, University of Naples Federico II, Naples, Italy.
Maria MaistoDepartment of Pharmacy, University of Naples Federico II, Naples, Italy.
Gian Carlo TenoreDepartment of Pharmacy, University of Naples Federico II, Naples, Italy.
Ettore NovellinoDepartment of Pharmacy, University of Naples Federico II, Naples, Italy.
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertriglyceridemia refers to the presence of elevated concentrations of triglycerides (TG) in the bloodstream (TG >200 mg/dL). This lipid alteration is known to be associated with an increased risk of atherosclerosis, contributing overall to the onset of atherosclerotic cardiovascular disease (CVD). Guidelines for the management of hypertriglyceridemia are based on both lifestyle intervention and pharmacological treatment, but poor adherence, medication-related costs and side effects can limit the success of these interventions. For this reason, the search for natural alternative approaches to reduce plasma TG levels currently represents a hot research field. This review article summarizes the most relevant clinical trials reporting the TG-reducing effect of different food-derived bioactive compounds. Furthermore, based on the evidence obtained from

Indexed as

cardiovascular riskfood-derived bioactive compoundshypertriglyceridemianutraceuticalobesity

Identifiers

PMID33330588
PMCPMC7734325
OpenAlexW3110352420

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.