Evidence map›Paper›PMID 33335859›Full record

ReviewFrontiers in oncology2020

The Role of Exosomes in Thyroid Cancer and Their Potential Clinical Application.

Kaixiang Feng, Runsheng Ma, Lele Zhang, Hongqiang Li, Yifeng Tang, Gongbo Du, Dongpeng Niu, Detao Yin

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Observational
  12. BRAFBiomedicines · 2022
    Article
  13. Review
  14. The Role of Exosomes and Their Applications in Cancer.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Review
  17. Review
  18. Molecular Chaperones and Thyroid Cancer.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kaixiang FengDepartment of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Runsheng MaDepartment of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lele ZhangDepartment of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Hongqiang LiDepartment of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yifeng TangDepartment of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Gongbo DuDepartment of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Dongpeng NiuDepartment of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Detao YinDepartment of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of thyroid cancer (TC) is rapidly increasing worldwide. The diagnostic accuracy and dynamics of TC need to be improved, and traditional treatments are not effective enough for patients with poorly differentiated thyroid cancer. Exosomes are membrane vesicles secreted specifically by various cells and are involved in intercellular communication. Recent studies have shown that exosomes secreted by TC cells contribute to tumor progression, angiogenesis and metastasis. Exosomes in liquid biopsies can reflect the overall molecular information of tumors, and have natural advantages in diagnosing TC. Exosomes also play an important role in tumor therapy due to their special physicochemical properties. TC patients will benefit as more exosome patterns are discovered. In this review, we discuss the role of TC-derived exosomes in tumorigenesis and development, and describe the application of exosomes in the diagnosis and treatment of TC.

Indexed as

biomarkerexosomeextracellular vesiclesoncology treatmentthyroid cancer

Identifiers

PMID33335859
PMCPMC7736410
OpenAlexW3109739581

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.