Evidence mapPaperPMID 33336181Full record

ArticleWorld journal of otorhinolaryngology - head and neck surgery2020

Endoscopic sinus surgery and aspirin desensitization improve otologic-specific SNOT-22 scores.

James G Naples, Andrew Corr, Siddhant Tripathi, Morgan Berman, Jason A Brant, Michael J Ruckenstein, John Bosso

Abstract read
In one paragraph

Article in World journal of otorhinolaryngology - head and neck surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. AERD: Quo Vadis?World journal of otorhinolaryngology - head and neck surgery · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

James G NaplesBeth Israel Deaconess Medical Center, Harvard Medical School, Division of Otolaryngology-Head and Neck Surgery, Otology/Neurotology, 110 Francis St, Suite 6E, Boston, MA 02215, USA.
Andrew CorrUniversity of Pennsylvania Health System, Department of Otorhinolaryngology-Head and Neck Surgery, Otology/Neurotology, 3400 Spruce St, 5 Silverstein, Philadelphia, PA 19104, USA.
Siddhant TripathiUniversity of Cincinnati School of Medicine, 230 Eden Ave, Cincinnati, OH 45267, USA.
Morgan BermanUniversity of Pennsylvania Health System, Department of Otorhinolaryngology-Head and Neck Surgery, Otology/Neurotology, 3400 Spruce St, 5 Silverstein, Philadelphia, PA 19104, USA.
Jason A BrantUniversity of Pennsylvania Health System, Department of Otorhinolaryngology-Head and Neck Surgery, Otology/Neurotology, 3400 Spruce St, 5 Silverstein, Philadelphia, PA 19104, USA.
Michael J RuckensteinUniversity of Pennsylvania Health System, Department of Otorhinolaryngology-Head and Neck Surgery, Otology/Neurotology, 3400 Spruce St, 5 Silverstein, Philadelphia, PA 19104, USA.
John BossoUniversity of Pennsylvania Health System, Department of Otorhinolaryngology-Head and Neck Surgery, Otology/Neurotology, 3400 Spruce St, 5 Silverstein, Philadelphia, PA 19104, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere are few studies evaluating the impact of Aspirin-exacerbated respiratory disease (AERD) treatment on otologic symptoms. The aim of this study is to evaluate the effects of endoscopic sinus surgery (ESS) and aspirin desensitization (AD) on otologic symptoms in subjects with AERD.

methodsRetrospective chart review of adult patients diagnosed with AERD at our tertiary Care Academic Medical Center - Otorhinolaryngology Department. Charts of adult patients diagnosed with AERD who underwent ESS and ASA desensitization at our institution's AERD Center from 2016 to 2019 were reviewed. Sino-Nasal Outcomes Test 22-item survey (SNOT-22) scores were evaluated for patients at various time points including: pre-surgery, post-surgery/pre-aspirin desensitization, and various times post-desensitization up to >12 months. Within the SNOT-22, otologic-specific subdomain scores were evaluated at similar time points. Patients on immunomodulatory medications other than corticosteroids were excluded from analysis.

resultsSNOT-22 scores were analyzed for 121 patients. There was a significant improvement in overall SNOT scores from pre-surgery (44.62) to post surgery/pre-desensitization (23.34) (

conclusionESS and AD reduce otologic-specific SNOT-22 scores and parallel trends in overall SNOT-22 scores. The effect of treatment is durable over the course of 12 months. Future work should aim to correlate otologic SNOT-22 scores with objective otologic data.

Indexed as

Aspirin exacerbated respiratory diseaseOtologic symptomsSNOT-22

Identifiers

PMID33336181
PMCPMC7729217

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.