Evidence map›Paper›PMID 33342709›Full record

SynthesisEpilepsy & behavior : E&B2021

Meta-analysis of EEG findings in patients with COVID-19.

Takafumi Kubota, Prasannakumar Kanubhai Gajera, Naoto Kuroda

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Epilepsy & behavior : E&B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 3 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 101 citations in OpenAlex.

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  19. [Subtle and subclinical neurological findings in patients with SARS-CoV-2].Revista medica del Instituto Mexicano del Seguro Social · 2023
    Observational
  20. Effects of COVID-19 on cognition and brain health.Trends in cognitive sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Takafumi KubotaDepartment of Neurology, University Hospitals of Cleveland Medical Center, Cleveland, USA; Department of Neurology, Case Western Reserve University, Cleveland, USA. Electronic address: takafumi.kubota@uhhospitals.org.
Prasannakumar Kanubhai GajeraDepartment of Neurology, University Hospitals of Cleveland Medical Center, Cleveland, USA; Department of Neurology, Case Western Reserve University, Cleveland, USA.
Naoto KurodaDepartment of Pediatrics, Wayne State University, Detroit, USA; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Japan.
University Hospitals of Cleveland · USWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo perform a systematic review and meta-analysis to summarize and quantitatively evaluate the electroencephalogram (EEG) findings in patients with coronavirus disease 2019 (COVID-19).

methodsThe MEDLINE, CENTRAL, and ClinicalTrials.Gov databases were comprehensively assessed and searched for observational studies with EEG findings in patients with COVID-19. Pooled proportions of EEG findings with 95% confidence intervals (CIs) were assessed using a random effects model. The quality of assessment for each study, heterogeneity between the studies, and publication bias were also evaluated.

resultsIn total, 12 studies with 308 patients were included in the meta-analysis. Abnormal background activity and generalized slowing in the pooled proportions were common findings among the patients with COVID-19 (96.1% [95% CI: 89.4-99.9]; I

conclusionThe proportion of abnormal background activity in patients with COVID-19 was high (96.1%). Epileptiform discharges were present in 20.3% of the cases and the proportion varied between people who had a history of epilepsy/seizure and those who did not. However, the proportion of seizures and status epilepticus on EEG was low (2.05% and 0. 80%, respectively).

Indexed as

Clinical Trials as TopicCOVID-19ElectroencephalographyEpilepsyHumansCOVID-19EEGEpilepsyNeurologySeizureStatus epilepticus

Identifiers

PMID33342709
PMCPMC7833461
OpenAlexW3112505925

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.