Evidence map›Paper›PMID 33343572›Full record

ArticleFrontiers in immunology2020

IL4I1 Accelerates the Expansion of Effector CD8

Marie-Line Puiffe, Aurélie Dupont, Nouhoum Sako, Jérôme Gatineau, José L Cohen, Denis Mestivier, Agnès Lebon, Armelle Prévost-Blondel, Flavia Castellano, Valérie Molinier-Frenkel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. bioRxiv : the preprint server for biology · 2025
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  10. Group AScience immunology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Marie-Line PuiffeVirus-Immunity-Cancer Department, Institut Mondor de Recherche Biomédicale (IMRB), INSERM U955, Université Paris-Est Créteil, Créteil, France.
Aurélie DupontVirus-Immunity-Cancer Department, Institut Mondor de Recherche Biomédicale (IMRB), INSERM U955, Université Paris-Est Créteil, Créteil, France.
Nouhoum SakoVirus-Immunity-Cancer Department, Institut Mondor de Recherche Biomédicale (IMRB), INSERM U955, Université Paris-Est Créteil, Créteil, France.
Jérôme GatineauVirus-Immunity-Cancer Department, Institut Mondor de Recherche Biomédicale (IMRB), INSERM U955, Université Paris-Est Créteil, Créteil, France.
José L CohenVirus-Immunity-Cancer Department, Institut Mondor de Recherche Biomédicale (IMRB), INSERM U955, Université Paris-Est Créteil, Créteil, France.
Denis MestivierBioinformatics Core Laboratory, Institut Mondor de Recherche Biomédicale (IMRB), INSERM U955, Université Paris-Est Créteil, Créteil, France.
Agnès LebonINSERM U1016, CNRS UMR8104, Institut Cochin, Université de Paris, Paris, France.
Armelle Prévost-BlondelINSERM U1016, CNRS UMR8104, Institut Cochin, Université de Paris, Paris, France.
Flavia CastellanoVirus-Immunity-Cancer Department, Institut Mondor de Recherche Biomédicale (IMRB), INSERM U955, Université Paris-Est Créteil, Créteil, France.
Valérie Molinier-FrenkelVirus-Immunity-Cancer Department, Institut Mondor de Recherche Biomédicale (IMRB), INSERM U955, Université Paris-Est Créteil, Créteil, France.
Institut Mondor de Recherche Biomédicale · FRUniversité Paris-Est Créteil · FRInserm · FRHôpital Albert-Chenevier · FRInstitut Cochin · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IL4I1 is an immunoregulatory enzyme that inhibits CD8 T-cell proliferation

Indexed as

Cell ProliferationImmunologic MemoryLymphocyte ActivationAcute DiseaseAnimalsCD8-Positive T-LymphocytesDendritic CellsImmunological SynapsesL-Amino Acid OxidaseLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMiceMice, KnockoutIl4i1 protein, mouseL-Amino Acid OxidaseCD8 T cellimmunosuppressive enzymelymphocytic choriomeningitis virusmemory precursor cellsT-cell activationT cell immune responseT-cell primingviral infection

Identifiers

PMID33343572
PMCPMC7746639
OpenAlexW3110498214

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.