Evidence map›Paper›PMID 33343676›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

An Investigation of the Molecular Mechanisms Underlying the Analgesic Effect of Jakyak-Gamcho Decoction: A Network Pharmacology Study.

Ho-Sung Lee, In-Hee Lee, Kyungrae Kang, Sang-In Park, Tae-Wook Kwon, Dae-Yeon Lee

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Network Pharmacology andCurrent pharmaceutical design · 2024
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ho-Sung LeeThe Fore, 87 Ogeum-ro, Songpa-gu, Seoul 05542, Republic of Korea.
In-Hee LeeThe Fore, 87 Ogeum-ro, Songpa-gu, Seoul 05542, Republic of Korea.
Kyungrae KangForest Hospital, 129 Ogeum-ro, Songpa-gu, Seoul 05549, Republic of Korea.
Sang-In ParkForestheal Hospital, 173 Ogeum-ro, Songpa-gu, Seoul 05641, Republic of Korea.
Tae-Wook KwonForest Hospital, 129 Ogeum-ro, Songpa-gu, Seoul 05549, Republic of Korea.
Dae-Yeon LeeThe Fore, 87 Ogeum-ro, Songpa-gu, Seoul 05542, Republic of Korea.ORCID https://orcid.org/0000-0002-3198-9881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herbal drugs have drawn substantial interest as effective analgesic agents; however, their therapeutic mechanisms remain to be fully understood. To address this question, we performed a network pharmacology study to explore the system-level mechanisms that underlie the analgesic activity of Jakyak-Gamcho decoction (JGd; Shaoyao-Gancao-Tang in Chinese and Shakuyaku-Kanzo-To in Japanese), an herbal prescription consisting of

Identifiers

PMID33343676
PMCPMC7732394

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.