Evidence map›Paper›PMID 33347772›Full record

ArticleJournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics

Effects of Glycyrrhizin Treatment on Diabetic Cornea.

Mallika Somayajulu, Sharon A McClellan, Ahalya Pitchaikannu, Denise Bessert, Li Liu, Jena Steinle, Linda D Hazlett

Open access · greenAbstract read
In one paragraph

Article in Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Healing Efficacy ofGels (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Systemic diseases and the cornea.Experimental eye research · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mallika SomayajuluDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
Sharon A McClellanDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
Ahalya PitchaikannuDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
Denise BessertDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
Li LiuDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
Jena SteinleDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
Linda D HazlettDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, Michigan, USA.
Wayne State University · US

Funding

Role of Toll-Like Receptors in Bacterial KeratitisR01EY016058 · NEI · WAYNE STATE UNIVERSITY · PI HAZLETT, LINDA D · 2005 to 2023
$6.0M
Inhibition of HMGB1 as a protective mechanism against diabetic retinopathyR01EY028442 · NEI · WAYNE STATE UNIVERSITY · PI STEINLE, JENA J · 2018 to 2021
$1.8M
NEI NIH HHS R01 EY016058NEI NIH HHS R01 EY028442
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAnimalsAnti-Inflammatory AgentsCell SurvivalCorneaDiabetes Mellitus, ExperimentalDisease Models, AnimalFemaleGlycyrrhizic AcidHumansInflammationMaleMiceMice, Inbred C57BLMiddle AgedOxidative StressAnti-Inflammatory AgentsGlycyrrhizic AcidStreptozocindiabetesglycyrrhizininflammationoxidative stress

Identifiers

PMID33347772
PMCPMC7826441
OpenAlexW3117455412

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.