Evidence mapPaperPMID 33348633Full record

ArticleChildren (Basel, Switzerland)2020

An Approach to Early Detection of Metabolic Syndrome through Non-Invasive Methods in Obese Children.

Rafael Molina-Luque, Natalia Ulloa, Andrea Gleisner, Martin Zilic, Manuel Romero-Saldaña, Guillermo Molina-Recio

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Rafael Molina-LuqueGrupo Asociado de Investigación Estilos de Vida, Innovación y Salud, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Córdoba, Spain.ORCID 0000-0002-5223-7400
Natalia UlloaCentro de Vida Saludable y Departamento de Bioquímica Clínica e Inmunología, Facultad de Farmacia, Universidad de Concepción, Concepción 4070386, Chile.ORCID 0000-0002-0437-5016
Andrea GleisnerDepartamento de Pediatría, Facultad de Medicina, Universidad de Concepción, Concepción 4070386, Chile.
Martin ZilicFacultad de Medicina, Universidad de Concepción, Concepción 4070386, Chile.
Manuel Romero-SaldañaGrupo Asociado de Investigación Estilos de Vida, Innovación y Salud, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Córdoba, Spain.ORCID 0000-0002-6146-4402
Guillermo Molina-RecioGrupo Asociado de Investigación Estilos de Vida, Innovación y Salud, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Córdoba, Spain.
Instituto Maimónides de Investigación Biomédica de Córdoba · ESUniversity of Concepción · CL

Funding

INNOVA CORFO 07CN131SM-19
6 · The paper itself

Abstract

backgroundMetabolic Syndrome (MetS) has a high prevalence in children, and its presence increases in those with a high BMI. This fact confirms the need for early detection to avoid the development of other comorbidities. Non-invasive variables are presented as a cost-effective and easy to apply alternative in any clinical setting.

aimTo propose a non-invasive method for the early diagnosis of MetS in overweight and obese Chilean children.

methodsWe conducted a cross-sectional study on 221 children aged 6 to 11 years. We carried out multivariate logistic regressions, receiver operating characteristic curves, and discriminant analysis to determine the predictive capacity of non-invasive variables. The proposed new method for early detection of MetS is based on clinical decision trees.

resultsThe prevalence of MetS was 26.7%. The area under the curve for the BMI and waist circumference was 0.827 and 0.808, respectively. Two decision trees were calculated: the first included blood pressure (≥104.5/69 mmHg), BMI (≥23.5 Kg/m

conclusionsEarly detection of MetS is possible through non-invasive methods in overweight and obese children. Two models (Clinical decision trees) based on anthropometric (non-invasive) variables with acceptable validity indexes have been presented. Clinical decision trees can be applied in different clinical and non-clinical settings, adapting to the tools available, being an economical and easy to measurement option. These methods reduce the use of blood tests to those patients who require confirmation.

Indexed as

anthropometrychildearly diagnosismetabolic syndromeobesity

Identifiers

PMID33348633
PMCPMC7767015
OpenAlexW3110872570

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.