Evidence mapPaperPMID 33348652Full record

ArticleInternational journal of molecular sciences2020

Adiponectin Exerts Peripheral Inhibitory Effects on the Mouse Gastric Smooth Muscle through the AMPK Pathway.

Eglantina Idrizaj, Rachele Garella, Silvia Nistri, Alfonso Dell'Accio, Emanuele Cassioli, Eleonora Rossi, Giovanni Castellini, Valdo Ricca, Roberta Squecco, Maria Caterina Baccari

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Nitric Oxide: From Gastric Motility to Gastric Dysmotility.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Eglantina IdrizajDepartment of Experimental & Clinical Medicine, Section of Physiological Sciences, University of Florence, 50134 Firenze, Italy.ORCID 0000-0002-2756-6552
Rachele GarellaDepartment of Experimental & Clinical Medicine, Section of Physiological Sciences, University of Florence, 50134 Firenze, Italy.ORCID 0000-0003-3194-7603
Silvia NistriDepartment of Experimental & Clinical Medicine, Research Unit of Histology & Embryology, University of Florence, 50139 Firenze, Italy.
Alfonso Dell'AccioDepartment of Biomedical, Experimental & Clinical Sciences "Mario Serio", University of Florence, 50134 Firenze, Italy.ORCID 0000-0001-6674-8781
Emanuele CassioliDepartment of Health Sciences, Psychiatry Unit, University of Florence, 50134 Firenze, Italy.ORCID 0000-0003-3623-7096
Eleonora RossiDepartment of Health Sciences, Psychiatry Unit, University of Florence, 50134 Firenze, Italy.ORCID 0000-0003-4755-3879
Giovanni CastelliniDepartment of Health Sciences, Psychiatry Unit, University of Florence, 50134 Firenze, Italy.
Valdo RiccaDepartment of Health Sciences, Psychiatry Unit, University of Florence, 50134 Firenze, Italy.ORCID 0000-0002-9291-2124
Roberta SqueccoDepartment of Experimental & Clinical Medicine, Section of Physiological Sciences, University of Florence, 50134 Firenze, Italy.
Maria Caterina BaccariDepartment of Experimental & Clinical Medicine, Section of Physiological Sciences, University of Florence, 50134 Firenze, Italy.ORCID 0000-0003-4665-1426
University of Florence · IT

Funding

Fondazione Ente Cassa di Risparmio di Firenze No. 2017.0777Fondazione Ente Cassa di Risparmio di Firenze No.2018.0994Università degli Studi di Firenze CO 090101010107-SQUECCO_ RICTD16Università degli Studi di Firenze RICATEN14
6 · The paper itself

Abstract

Some adipokines, such as adiponectin (ADPN), other than being implicated in the central regulation of feeding behavior, may influence gastric motor responses, which are a source of peripheral signals that also influence food intake. The present study aims to elucidate the signaling pathways through which ADPN exerts its actions in the mouse gastric fundus. To this purpose, we used a multidisciplinary approach. The mechanical results showed that ADPN caused a decay of the strip basal tension, which was abolished by the nitric oxide (NO) synthesis inhibitor, L-N

Indexed as

AdiponectinAMP-Activated Protein KinasesAnimalsFemaleGastric FundusGastric MucosaMiceMice, Inbred C57BLMuscle, SmoothObesityPyrazolesPyrimidinesReceptors, AdiponectinSignal TransductionAdiponectinadiponectin receptor 1, mouseAMP-Activated Protein KinasesdorsomorphinPyrazolesPyrimidinesReceptors, AdiponectinadiponectinAdipoR1AMPKcell excitabilitycell signalinggastric fundusmechanical activity

Identifiers

PMID33348652
PMCPMC7767160
OpenAlexW3110849553

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.