Evidence map›Paper›PMID 33352286›Full record

ReviewNeuroscience letters2021

Neurological issues in children with COVID-19.

Jieru E Lin, Arsenoi Asfour, Taylor B Sewell, Benjamin Hooe, Patrice Pryce, Chelsea Earley, Min Ye Shen, Mallory Kerner-Rossi, Kiran T Thakur, Wendy S Vargas and 2 more

Abstract readReview
In one paragraph

Review in Neuroscience letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Trace elements and metal nanoparticles: mechanistic approaches to mitigating chemotherapy-induced toxicity-a review of literature evidence.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Review
  8. Article
  9. Isolated Sixth Nerve Palsy and COVID-19: A Recurrent Case in a 7-Month-Old Child and Analysis of Reported Cases.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2024
    Review
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52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jieru E LinDepartment of Neurology, Division of Child Neurology, Columbia University Irving Medical Center, New York, NY 10032, United States; Department of Pediatrics, Columbia University Irving Medical Center, Morgan Stanley Children's Hospital, New York, NY 10032, United States.
Arsenoi AsfourDepartment of Neurology, Division of Child Neurology, Columbia University Irving Medical Center, New York, NY 10032, United States; Department of Pediatrics, Columbia University Irving Medical Center, Morgan Stanley Children's Hospital, New York, NY 10032, United States.
Taylor B SewellDepartment of Pediatrics, Division of Pediatric Critical Care and Hospital Medicine, Columbia University Irving Medical Center, New York, NY 10032, United States.
Benjamin HooeDepartment of Pediatrics, Division of Pediatric Critical Care and Hospital Medicine, Columbia University Irving Medical Center, New York, NY 10032, United States.
Patrice PryceDepartment of Pediatrics, Division of Pediatric Critical Care and Hospital Medicine, Columbia University Irving Medical Center, New York, NY 10032, United States.
Chelsea EarleyDepartment of Neurology, Division of Child Neurology, Columbia University Irving Medical Center, New York, NY 10032, United States; Department of Pediatrics, Columbia University Irving Medical Center, Morgan Stanley Children's Hospital, New York, NY 10032, United States.
Min Ye ShenDepartment of Neurology, Division of Child Neurology, Columbia University Irving Medical Center, New York, NY 10032, United States; Department of Pediatrics, Columbia University Irving Medical Center, Morgan Stanley Children's Hospital, New York, NY 10032, United States.
Mallory Kerner-RossiDepartment of Neurology, Division of Child Neurology, Columbia University Irving Medical Center, New York, NY 10032, United States; Department of Pediatrics, Columbia University Irving Medical Center, Morgan Stanley Children's Hospital, New York, NY 10032, United States.
Kiran T ThakurDepartment of Neurology, Columbia University Irving Medical Center, New York, NY 10032, United States.
Wendy S VargasDepartment of Neurology, Division of Child Neurology, Columbia University Irving Medical Center, New York, NY 10032, United States.
Wendy G SilverDepartment of Neurology, Division of Child Neurology, Columbia University Irving Medical Center, New York, NY 10032, United States.
Andrew S GeneslawDepartment of Pediatrics, Division of Pediatric Critical Care and Hospital Medicine, Columbia University Irving Medical Center, New York, NY 10032, United States. Electronic address: asg2195@cumc.columbia.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) usually leads to a mild infectious disease course in children, but serious complications may occur in conjunction with both acute infection and associated phenomena such as the multisystem inflammatory syndrome in children (MIS-C). Neurological symptoms, which have been predominantly reported in adults, range from mild headache to seizure, peripheral neuropathy, stroke, demyelinating disorders, and encephalopathy. Similar to respiratory and cardiac manifestations of COVID-19, neurological complications present differently based on age and underlying comorbidities. This review provides a concise overview of the neurological conditions seen in the context of COVID-19, as well as potential mechanisms and long-term implications of COVID-19 in the pediatric population from literature reviews and primary data collected at NewYork-Presbyterian Morgan Stanley Children's Hospital.

Indexed as

ChildChild, PreschoolCOVID-19FemaleHumansMaleNervous System DiseasesSARS-CoV-2COVID-19Multisystem inflammatory syndrome in children (MIS-C)PediatricsSARS-CoV-2

Identifiers

PMID33352286
PMCPMC7831718

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.