Evidence map›Paper›PMID 33353117›Full record

ReviewAntioxidants (Basel, Switzerland)2020

Hydrogen Sulfide and Carnosine: Modulation of Oxidative Stress and Inflammation in Kidney and Brain Axis.

Vittorio Calabrese, Maria Scuto, Angela Trovato Salinaro, Giuseppe Dionisio, Sergio Modafferi, Maria Laura Ontario, Valentina Greco, Sebastiano Sciuto, Claus Peter Schmitt, Edward J Calabrese and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Urinary metabolomics profile in children with ureteropelvic junction obstruction.Metabolomics : Official journal of the Metabolomic Society · 2026
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  13. Energy metabolism in health and diseases.Signal transduction and targeted therapy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Vittorio CalabreseDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95125 Catania, Italy.ORCID 0000-0002-0478-985X
Maria ScutoDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95125 Catania, Italy.ORCID 0000-0003-1019-5158
Angela Trovato SalinaroDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95125 Catania, Italy.ORCID 0000-0003-2377-858X
Giuseppe DionisioDepartment of Molecular Biology and Genetics, Research Center Flakkebjerg, Aarhus University, Forsøgsvej 1, 4200 Slagelse, Denmark.ORCID 0000-0003-4416-0519
Sergio ModafferiDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95125 Catania, Italy.ORCID 0000-0002-9441-0507
Maria Laura OntarioDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95125 Catania, Italy.
Valentina GrecoDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95125 Catania, Italy.ORCID 0000-0002-6694-2151
Sebastiano SciutoDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95125 Catania, Italy.ORCID 0000-0002-8557-9386
Claus Peter SchmittCentre for Pediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.
Edward J CalabreseDepartment of Environmental Health Sciences, Morrill I, N344, University of Massachusetts, Amherst, MA 01003, USA.
Verena PetersCentre for Pediatric and Adolescent Medicine, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-4649-0848
University of Catania · ITHeidelberg University · DEAarhus University · DKUniversity of Massachusetts Amherst · US

Funding

Piano Ricerca Triennale-linea Intervento 2-University of Catania. PRT 2019
6 · The paper itself

Abstract

Emerging evidence indicates that the dysregulation of cellular redox homeostasis and chronic inflammatory processes are implicated in the pathogenesis of kidney and brain disorders. In this light, endogenous dipeptide carnosine (β-alanyl-L-histidine) and hydrogen sulfide (H

Indexed as

carnosinehydrogen sulfideinflammationkidney–brain axisoxidative stressvitagenes

Identifiers

PMID33353117
PMCPMC7767317
OpenAlexW3110894228

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.