Evidence map›Paper›PMID 33356011›Full record

Trial reportPhysiological reports2021

α-Adrenergic receptor blockade attenuates pressor response during mental stress in young black adults.

Jin Hee Jeong, Michelle L Brown, Gaston Kapuku, Gregory A Harshfield, Jeanie Park

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jin Hee JeongDepartment of Medicine, Georgia Prevention Institute, Medical College of Georgia, Augusta University, Augusta, GA, USA.ORCID 0000-0002-8748-8429
Michelle L BrownDepartment of Medicine, Georgia Prevention Institute, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Gaston KapukuDepartment of Medicine, Georgia Prevention Institute, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Gregory A HarshfieldDepartment of Medicine, Georgia Prevention Institute, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Jeanie ParkDivision of Renal Medicine, Department of Medicine, Emory University, Atlanta, GA, USA.ORCID 0000-0002-5799-9172
Augusta University · USEmory University · US

Funding

Vascular and renal responses to stressP01HL069999 · NHLBI · MEDICAL COLLEGE OF GEORGIA (MCG) · PI GEORGE, VARGHESE · 2002 to 2018
$31.1M
Neurovascular Regulation During Exercise In Humans With Chronic Kidney DiseaseR01HL135183 · NHLBI · EMORY UNIVERSITY · PI Jeanie Park · 2017 to 2026
$5.4M
Sympatho-inhibition with Mindfulness in Chronic Kidney DiseaseR61AT010457 · NCCIH · EMORY UNIVERSITY · PI PARK, JEANIE · 2019 to 2020
$946k
Mechanisms of Sympathetic Overactivity in Post-traumatic Stress DisorderI01CX001065 · VA · VETERANS HEALTH ADMINISTRATION · PI PARK, JEANIE · 2015 to 2024
–
CSRD VA I01 CX001065NCCIH NIH HHS R61 AT010457NHLBI NIH HHS P01 HL069999NHLBI NIH HHS R01 HL135183VA I01CX001065
6 · The paper itself

Abstract

Black individuals exhibit increased blood pressure (BP) responses to sympathetic stimulation that are associated with an increased risk of hypertension (HTN). We tested the hypothesis that α

Indexed as

Adrenergic alpha-1 Receptor AntagonistsAdultBlack PeopleBlood PressureFemaleHumansMalePrazosinReflexSodiumStress, PsychologicalAdrenergic alpha-1 Receptor AntagonistsPrazosinSodiumBlacksHypertensionMental Stressα-Adrenergic Receptor Blocker

Identifiers

PMID33356011
PMCPMC7757373
OpenAlexW3116063658

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.