Evidence map›Paper›PMID 33356554›Full record

ArticleEpigenomics2021

Epigenetic targeting of Waldenström macroglobulinemia cells with BET inhibitors synergizes with BCL2 or histone deacetylase inhibition.

Stephan J Matissek, Weiguo Han, Mona Karbalivand, Mohamed Sayed, Brendan M Reilly, Shayna Mallat, Shimaa M Ghazal, Manit Munshi, Guang Yang, Steven P Treon and 2 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epigenomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Stephan J MatissekDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH, 03824, USA.ORCID 0000-0001-6236-8837
Weiguo HanDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH, 03824, USA.ORCID 0000-0003-4842-4833
Mona KarbalivandDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH, 03824, USA.ORCID 0000-0003-0668-5111
Mohamed SayedDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH, 03824, USA.ORCID 0000-0001-8011-8110
Brendan M ReillyDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH, 03824, USA.ORCID 0000-0003-3975-9623
Shayna MallatDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH, 03824, USA.
Shimaa M GhazalDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH, 03824, USA.ORCID 0000-0002-8004-8228
Manit MunshiBing Center for Waldenström Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
Guang YangBing Center for Waldenström Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.ORCID 0000-0003-3049-4200
Steven P TreonBing Center for Waldenström Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.ORCID 0000-0001-6393-6154
Sarah R WalkerDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH, 03824, USA.ORCID 0000-0001-6465-241X
Sherine F ElsawaDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH, 03824, USA.ORCID 0000-0002-3917-3078

Funding

TLR-TRIF mediated induction of GLI3 modulates innate inflammatory responsesP20GM113131 · NIGMS · UNIVERSITY OF NEW HAMPSHIRE · PI Sean Stoddart Coleman Edington · 2017 to 2026
$22.8M
NIGMS NIH HHS P20 GM113131
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenineAntineoplastic AgentsBridged Bicyclo Compounds, HeterocyclicCell Line, TumorEpigenesis, GeneticHistone Deacetylase InhibitorsHistone DeacetylasesHumansLymphoma, B-CellMolecular Targeted TherapyNerve Tissue ProteinsPiperidinesProtein Kinase InhibitorsProto-Oncogene Proteins c-bcl-2Receptors, Cell SurfaceSulfonamidesAdenineAntineoplastic AgentsBCL2 protein, humanBridged Bicyclo Compounds, HeterocyclicDNER protein, humanHistone Deacetylase InhibitorsHistone DeacetylasesibrutinibNerve Tissue ProteinsPiperidinesProtein Kinase InhibitorsProto-Oncogene Proteins c-bcl-2Receptors, Cell SurfaceSulfonamidesvenetoclaxBET inhibitorsepigeneticspanobinostatvenetoclaxWaldenström macroglobulinemia

Identifiers

PMID33356554
PMCPMC8656319

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.